Implantable Pump with Accumulator for Tuned Bolus Delivery
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Solution Overview
Problem
Current implantable medical pumps lack the ability to deliver medicaments over a wide range of velocities and volumes with precision, limiting their customization and effectiveness in treating various medical conditions.
Innovation Solution
The development of an implantable pump system that combines a peristaltic pump with an accumulator and valve, allowing for both steady-state and bolus medicament delivery, enabling tuning of delivery velocities and volumes, and incorporating a computing device to sense electromotive force voltage and pressure for occlusion detection and calibration.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If a peristaltic pump is used for steady-state medicament delivery, then delivery precision is improved, but the ability to deliver boluses at higher velocities is limited
Solution Approach 1:
The system is divided into two functional components: a peristaltic pump for precise steady-state delivery and an accumulator for bolus delivery. This segmentation allows each component to optimize its specific function while working together to provide both precision and high velocity capabilities.
Solution Approach 2:
The accumulator acts as an intermediary between the peristaltic pump and the delivery catheter. It receives medicament from the pump and can release it rapidly as a bolus, mediating between the pump's steady-state output and the need for high-velocity delivery.
2Measurement precision
If the pump operates at low velocity for precision delivery, then delivery precision is improved, but the range of deliverable velocities is limited
Solution Approach 1:
The system dynamically switches between two delivery modes: steady-state low-velocity delivery through the peristaltic pump and high-velocity bolus delivery through the accumulator. This dynamic operation allows the system to adapt to different clinical requirements while maintaining precision in both modes.
Solution Approach 2:
The combined pump-accumulator system provides multiple delivery functions: continuous steady-state infusion, intermittent bolus delivery, and programmable delivery patterns. This multi-functionality expands the velocity range while maintaining precision through the peristaltic pump's controlled operation.
3Device complexity
If a single pump mechanism is used, then device complexity is reduced, but the ability to deliver medicament over a wide range of velocities and volumes is limited
Solution Approach 1:
The peristaltic pump and accumulator are merged into a single integrated implantable device with shared housing, power source, and control electronics. This combination provides diverse delivery capabilities (steady-state and bolus) while maintaining a compact single-device form factor.
Solution Approach 2:
The accumulator is nested within the pump housing, with the pump positioned to deliver medicament into the accumulator. This nested arrangement allows both components to occupy minimal space while providing combined functionality, expanding the delivery range without proportionally increasing device complexity.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This system enables precise delivery of medicaments over a wider range of velocities and volumes, improving therapeutic efficacy and allowing for real-time monitoring and detection of potential issues such as catheter occlusion, while maintaining precision and reducing patient compliance risks.
Implementation Method 1
The techniques of this disclosure generally relate to optionally pulsatile flow generating implantable systems and pumps including a peristaltic pump configured to precisely deliver steady state flow of medicament
Implementation Method 2
a combination accumulator and valve configured to selectively deliver larger boluses
Data Source
Figure 1
Figure 2A~2B
Figure 3
AI summary
An implantable pump configured to enable tuning of a delivery velocity of a fixed quantity of medicament. The implantable pump including a pump, an accumulator and a valve configured to enable tuning of a delivery velocity of a fixed quantity of medicament, wherein operating the pump with the valve continuously in the open state enables a steady-state delivery of medicament at a first velocity, and wherein closing of the valve enables the pump to at least partially fill the accumulator and subsequent opening of the valve enables the at least partially filled accumulator to dispense medicament, thereby delivering a bolus of medicament at a second velocity, wherein the second velocity is greater than the first velocity.