Implantable RF Sensor for Continuous Fluid Monitoring

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Solution Overview

Problem

Current methods for monitoring fluid accumulation in and around body organs over extended periods are limited in accuracy and convenience, particularly for chronic medical conditions like pulmonary edema and pericardial effusion, as they often require invasive procedures and lack continuous, reliable tracking.

Innovation Solution

Implantable devices with biocompatible antennas and processing circuitry that use RF electromagnetic waves to measure tissue characteristics, such as fluid content, by transmitting and receiving waves through or reflected from target tissues, and reporting data wirelessly for continuous monitoring.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If external RF monitoring apparatus is used, then measurement capability is provided, but patient mobility is restricted and long-term monitoring accuracy deteriorates

Engineering Contradiction:
Improvemonitoring accuracyVSAvoidpatient convenience
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The RF transmitter and antenna are integrated within an implantable medical device (such as a pacemaker or defibrillator), nesting the monitoring function inside an existing implanted device. This eliminates the need for external monitoring apparatus while maintaining measurement capability and improving patient mobility.

Inventive Principle:
Principle #7Nested doll (Nesting)

2Measurement precision

If invasive procedures are used for fluid monitoring, then measurement precision is improved, but patient discomfort and procedural complexity increase

Engineering Contradiction:
Improvefluid content measurement accuracyVSAvoidprocedural complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The RF transmitter serves multiple functions: it transmits RF waves for fluid content measurement, provides cardiac stimulation therapy, and enables communication. By making the implanted device multi-functional, the system achieves precise fluid monitoring without requiring separate invasive procedures or additional complex equipment.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables long-term, accurate monitoring of fluid levels in organs like the lungs, allowing for timely adjustments in treatment and improved patient management, with the potential for application in other tissue monitoring and imaging applications.

Implementation Method 1

receive radio frequency (RF) electromagnetic waves propagated through the target tissue

Methodology Applied
Scientific EffectElectromagnetic wave propagation: Electromagnetic Induction

Implementation Method 2

A change of a dielectric coefficient of the thoracic tissue is detected by analyzing the reflections

Methodology Applied
Scientific EffectDielectric property detection: Dielectric

Implementation Method 3

receive the waves after reflection of the waves from a tissue in the body

Methodology Applied
Scientific EffectWave reflection: Reflection

Implementation Method 4

detect a modulation of the reflection due to at least one of a heartbeat and a respiratory motion of the subject

Methodology Applied
Scientific EffectFrequency modulation detection: Phase Modulation

Data Source

PatentUS10136833B2Implantable radio-frequency sensor
Publication Date: 2018.11.27 ZOLL MEDICAL ISRAEL LTD
  • US10136833B2 patent drawing
  • US10136833B2 patent drawing
  • US10136833B2 patent drawing

AI summary

A diagnostic apparatus comprising a sealed case, a first antenna and a second antenna and processing circuitry are disclosed herein. In some embodiments, the sealed case includes a biocompatible material and is configured for implantation within a body of a patient. Further, each one of the first antenna and the second antenna are configured to be implanted in the body in proximity to a target tissue, generate and transmit radio frequency (RF) electromagnetic waves through the target tissue to the other antenna, and output a signal in response to RF waves received from the other antenna. In addition, the processing circuitry can be contained within the case and is configured to receive and process the signal from each antenna so as to derive and output an indication of a characteristic of the target tissue.