Implantable Sensor Element With Transparent Coupling Part

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Solution Overview

Problem

Conventional sensor elements for detecting analytes in body fluids or tissues face challenges with mechanical stability and ease of implantation, particularly due to the fragility of optical waveguides and the need for complex production processes that can lead to tissue damage during implantation and removal.

Innovation Solution

A one-piece, implantable sensor element with an optically transparent coupling part that serves as a 'window' for optical coupling, eliminating the need for separate optical waveguides and ensuring mechanical stability, and a method for producing this element using crosslinkable polymers that can be cured in situ, allowing for a simpler and more reliable implantation process.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If separate optical waveguides are used for optical coupling, then optical signal transmission is achieved, but mechanical stability deteriorates due to waveguide fragility

Engineering Contradiction:
Improveoptical signal transmissionVSAvoidmechanical stability
Core Design Contradiction:
ReliabilityVSStrength

Solution Approach 1:

The patent integrates the optical waveguide function directly into the sensor element body by forming an optically transparent coupling part from the same polymeric material. This merging eliminates separate waveguide components and their vulnerable connection points, providing both optical signal transmission and mechanical stability through a unified structure.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The sensor element is divided into distinct functional zones: a sensor area with sensor material for analyte detection and a coupling part with optically transparent material for light transmission. This segmentation allows each zone to be optimized for its specific function while maintaining overall mechanical integrity through the polymeric matrix.

Inventive Principle:
Principle #1Segmentation

2Reliability

If complex production processes are used for sensor element manufacturing, then sensor functionality is achieved, but ease of manufacture deteriorates

Engineering Contradiction:
Improvesensor functionalityVSAvoidproduction process simplicity
Core Design Contradiction:
ReliabilityVSEase of manufacture

Solution Approach 1:

The manufacturing process combines multiple functions into a single polymeric matrix formulation. The matrix material simultaneously provides structural support, optical transparency for light transmission, and a medium for embedding sensor material. This consolidation eliminates separate manufacturing steps for waveguide assembly and sensor integration, significantly simplifying production.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent utilizes the optical properties of the polymeric matrix material itself rather than requiring separate waveguide materials. By selecting a matrix with appropriate optical transparency and mechanical properties, the invention achieves optical coupling functionality through material parameter selection rather than complex structural assembly.

Inventive Principle:
Principle #35Parameter changes

3Ease of operation

If conventional implantation methods are used, then sensor implantation is achieved, but tissue damage increases due to mechanical stress on fragile components

Engineering Contradiction:
Improveimplantation processVSAvoidtissue damage
Core Design Contradiction:
Ease of operationVSObject-affected harmful factors

Solution Approach 1:

The sensor element is designed as a compact, self-contained unit with integrated optical and sensing functions. This segmentation into a single implantable component eliminates the need for separate waveguide connections during implantation, reducing mechanical stress and tissue damage while maintaining ease of implantation through a minimally invasive procedure.

Inventive Principle:
Principle #1Segmentation

4Reliability

If separate optical waveguides are used for coupling, then optical coupling is achieved, but device complexity increases

Engineering Contradiction:
Improveoptical couplingVSAvoidnumber of components
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The invention merges the optical waveguide function with the sensor element structure by using the polymeric matrix material itself as the optically transparent coupling medium. This integration reduces the device to a single component with embedded sensing functionality, eliminating multiple separate parts and their associated assembly complexity while maintaining reliable optical coupling.

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The solution provides a mechanically stable and painless implantation method for sensor elements, reducing tissue damage and simplifying the production process, while maintaining accurate optical coupling for analyte detection.

Implementation Method 1

configured to transmit electromagnetic radiation in at least one spectral range between the sensor area and the coupling end

Methodology Applied
Scientific EffectElectromagnetic radiation transmission: Light

Implementation Method 2

comprises at least one sensor material which, in the presence of one or more specific analytes, alters at least one optically measurable property

Methodology Applied
Scientific EffectOptical property change: Absorption (EM radiation)

Implementation Method 3

The matrix material comprises at least one crosslinkable polymer, in particular a biocompatible crosslinkable polymer, in crosslinked form

Methodology Applied
Scientific EffectCrosslinking: Chemical Bonding

Data Source

PatentEP2334236B1Implantable sensor element
Publication Date: 2019.04.24 EYESENSE AG
  • EP2334236B1 patent drawingFigure 1
  • EP2334236B1 patent drawingFigure 2A~2F
  • EP2334236B1 patent drawingFigure 3A~3C

AI summary

A sensor element (110) comprises an implantable, single-piece molded body (112), which comprises a sensor end (114) and a coupling end (116). The molded body comprises a sensor area (118) in the sensor end region, which comprises a sensor material (122). The sensor material modifies an optically measurable property in presence of analytes. The molded body also comprises an optically transparent coupling part (120), which is adapted to transmit electromagnetic radiation to a spectral range between the sensor area and the coupling end. A sensor element comprises an implantable, single-piece molded body, which comprises a sensor end and a coupling end. The molded body comprises a sensor area in the sensor end region, which comprises a sensor material. The sensor material modifies an optically measurable property in presence of analytes. The molded body also comprises an optically transparent coupling part, which is adapted to transmit electromagnetic radiation to a spectral range between the sensor area and the coupling end. The molded body additionally comprises an optically transparent matrix material (124) in the sensor area. The analyte can diffuse partially through the matrix material to the sensor material. The sensor material is embedded in the matrix material. The coupling part is partially formed by the matrix material. Independent claims are included for: (1) a sensor arrangement, which comprises sensor element and optical detectors, which are equipped to a body tissue; and (2) a method for preparing sensor element, which involves introducing prepolymer liquid into a cannula with a curable prepolymer to prepare optically transparent coupling part.