Implanted Stimulator Promoting Neural Remodeling
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Solution Overview
Problem
Current methods fail to effectively address excess or faulty neural connections in the brain, which are linked to disorders such as autism, schizophrenia, and depression, as they do not adequately promote neural remodeling or repair.
Innovation Solution
An implanted stimulator applies specific stimuli, including electrical, drug, gene, chemical, thermal, or electromagnetic stimulation, to promote neural remodeling by inducing dedifferentiation and redifferentiation of neural connections, targeting areas like the temporal lobe, limbic system, and cerebral cortex.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional treatment methods are used, then existing medical conditions are addressed, but excess or faulty neural connections are not effectively removed or repaired
Solution Approach 1:
The patent applies electrical stimulation with specific parameters (amplitude, frequency, pulse width) to induce neural dedifferentiation and redifferentiation. By changing the electrical parameters of stimulation, the system promotes neural remodeling to remove excess connections and repair faulty connections, directly addressing the inadequacy of conventional treatment methods in achieving effective neural repair
2Reliability
If neural remodeling is promoted through multiple stimulation types, then neural connection repair is enhanced, but device complexity increases
Solution Approach 1:
The implantable stimulator is designed as a multi-functional device capable of delivering various stimulation types (electrical, drug, gene, chemical, thermal, electromagnetic) through a single integrated system. This universal approach allows the device to promote neural remodeling through multiple mechanisms while maintaining a unified device architecture, thereby enhancing neural repair effectiveness without proportionally increasing device complexity
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This approach enables the removal and repair of faulty neural connections, potentially treating a range of medical conditions by promoting normal neural development and function, thereby improving symptoms associated with disorders like autism and depression.
Implementation Method 1
The at least one stimulus is configured to promote neural remodeling and may include electrical stimulation, drug stimulation, gene infusion, chemical stimulation, thermal stimulation, electromagnetic stimulation, and/or any other suitable stimulation.
Implementation Method 2
The at least one stimulus is configured to promote neural remodeling and may include electrical stimulation, drug stimulation, gene infusion, chemical stimulation, thermal stimulation, electromagnetic stimulation, and/or any other suitable stimulation.
Implementation Method 3
The at least one stimulus is configured to promote neural remodeling and may include electrical stimulation, drug stimulation, gene infusion, chemical stimulation, thermal stimulation, electromagnetic stimulation, and/or any other suitable stimulation.
Data Source
AI summary
Methods of treating a medical condition include applying at least one stimulus to a stimulation site within the brain of a patient with an implanted stimulator in accordance with one or more stimulation parameters. The at least one stimulus is configured to promote neural remodeling within the brain of the patient. Systems for treating a medical condition include an implantable stimulator configured to apply at least one stimulus to a stimulation site within the brain of a patient in accordance with one or more stimulation parameters. The at least one stimulus is configured to promote neural remodeling within the brain of the patient.