In Vivo Glucose Sensor Compensation for Temperature-Driven Errors

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Solution Overview

Problem

In vivo analyte sensors, such as glucose sensors, are affected by temperature changes, leading to measurement errors that impact the accuracy of analyte readings.

Innovation Solution

Implementing temperature compensation methods using temperature sensors to adjust glucose readings based on temperature thresholds or ranges, ensuring accurate analyte measurement by compensating for ambient or core body temperature fluctuations.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If temperature compensation is implemented using temperature sensors and processing, then measurement precision is improved, but device complexity increases

Engineering Contradiction:

Improveanalyte measurement accuracyVSAvoidsystem complexity

Core Design Contradiction:

Measurement precisionVSDevice complexity

Solution Approach 1:

The patent applies preliminary action by pre-determining temperature compensation factors and algorithms before actual analyte measurement. Temperature sensors continuously monitor and pre-calculate compensation values, which are then applied to correct analyte readings in real-time, eliminating the need for complex real-time temperature analysis during measurement.

Inventive Principle:

Principle #10Preliminary action

Solution Approach 2:

The patent uses temperature sensors as intermediary elements that mediate between the physical temperature environment and the analyte measurement system. These sensors convert temperature variations into electrical signals that the processor can interpret and use to apply appropriate compensation algorithms, simplifying the overall system architecture.

Inventive Principle:

Principle #24Intermediary (Mediator)

2Reliability

If temperature sensors and compensation processing are added, then reliability is improved, but device complexity increases

Engineering Contradiction:

Improvemeasurement reliabilityVSAvoidsystem complexity

Core Design Contradiction:

ReliabilityVSDevice complexity

Solution Approach 1:

The system applies self-service by automatically performing temperature compensation without requiring manual intervention. The processor continuously monitors temperature sensor data, automatically selects appropriate compensation algorithms, and applies corrections to analyte measurements in real-time, ensuring reliable operation while maintaining simple user interaction.

Inventive Principle:

Principle #25Self-service

Solution Approach 2:

The patent implements feedback mechanisms where temperature sensor readings continuously feed into the processor, which then adjusts compensation parameters and applies them to analyte measurements. This closed-loop feedback system ensures that temperature variations are automatically compensated, improving reliability while using straightforward control logic.

Inventive Principle:

Principle #23Feedback

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The method provides accurate and reliable analyte measurements by minimizing temperature-induced errors, enhancing the precision of glucose monitoring systems.

Implementation Method 1

determining a temperature of an environment surrounding an in vivo glucose sensor

Methodology Applied

Scientific EffectTemperature sensing:

Data Source

PatentEP3556285B2Temperature-compensated analyte monitoring devices, systems, and methods thereof

Publication Date: 2026.03.18 ABBOTT DIABETES CARE INC

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AI summary

Methods, devices and systems related providing accurate glucose levels in view of temperatures that may adversely affect glucose value.