Inclined NMR Sample Changer for Ergonomic Loading

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Solution Overview

Problem

Ergonomically unfavorable sample loading and changing in NMR spectrometers, particularly in benchtop devices, due to the device's height and dimensions, leading to strenuous and uncomfortable operations for operators.

Innovation Solution

A sample changer with a two-part tandem rocker or cone carousel design, where the sample holder's axis of rotation is inclined between 30 and 60 degrees, allowing for easier sample access and handling, and featuring a funnel-shaped opening, electrically controlled blocking device, and pneumatic sample transfer to improve ergonomics and automation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If the NMR spectrometer is designed with a vertically oriented receiving opening for samples, then the measurement function is achieved, but the operator experiences ergonomic strain due to extended arm reach

Engineering Contradiction:
Improveergonomics of sample loadingVSAvoidheight of receiving opening
Core Design Contradiction:
Ease of operationVSLength of stationary object

Solution Approach 1:

The sample holder is tilted at an angle of 30-60 degrees relative to the vertical axis, changing the dimensional orientation of sample insertion from a purely vertical path to an inclined path. This allows the operator to access samples at a more ergonomic height and angle while the sample holder mechanically bridges the gap to the vertical receiving opening, resolving the contradiction between measurement geometry and operator comfort

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

2Ease of operation

If the sample holder is tilted at an angle of 30-60 degrees for ergonomic loading, then operator comfort is improved, but the sample axis must be realigned to vertical for measurement

Engineering Contradiction:
Improveease of sample handlingVSAvoidsample positioning mechanism
Core Design Contradiction:
Ease of operationVSDevice complexity

Solution Approach 1:

The sample holder is designed to be rotatable about its cylindrical axis, transforming from a static inclined structure to a dynamic element that can change orientation. This allows the sample holder to be tilted for ergonomic loading during sample insertion, then rotated to align the sample axis vertically for measurement, accommodating both ergonomic and measurement requirements through dynamic reconfiguration

Inventive Principle:
Principle #15Dynamics

3Productivity

If automatic sample changers are used to increase throughput, then productivity is improved, but the device complexity and cost increase

Engineering Contradiction:
Improvesample throughputVSAvoidsample changer mechanism
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The sample changer is divided into multiple independent sample holders (at least two), each capable of holding and transferring samples independently. This segmentation allows automated or semi-automated operation where multiple samples can be loaded and transferred without requiring the operator to manually insert each sample individually, increasing throughput while keeping each individual sample holder relatively simple in design

Inventive Principle:
Principle #1Segmentation

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Significantly improves ergonomics and handling ease for operators, prevents sample fluid loss and uneven measuring signals, and simplifies the measurement process by allowing automatic sample changing and gentle pneumatic transfer.

Implementation Method 1

the sample holder is mounted such that the cylindrical axis of the cylindrical sample holder of the sample changer is inclined at the loading position by an angle of inclination α between 30 and 60 degrees to the vertical, while, after a rotation, it runs vertically into the transfer position

Methodology Applied
Scientific EffectRotation:

Implementation Method 2

a positioning device is provided which transfers the NMR sample at the transfer position or after passing through it into the measuring position in the measuring volume with a vertically oriented sample axis of the NMR sample

Methodology Applied
Scientific EffectGravitation: Gravitation

Data Source

PatentEP2843436B1NMR spectrometer with ergonomically favourable sample exchanger
Publication Date: 2019.07.17 BRUKER BIOSPIN GMBH
  • EP2843436B1 patent drawingFigure 1a
  • EP2843436B1 patent drawingFigure 1b
  • EP2843436B1 patent drawingFigure 2a

AI summary

An NMR spectrometer (1') comprising a magnet arrangement (2) with a vertically oriented upper receiving opening for receiving an NMR sample extending along a sample axis and a measuring volume (3) in which the elongated NMR sample is positioned in a measuring position with a vertically oriented sample axis during the performance of an NMR measurement, and with a sample changer (4') having at least one cylindrical sample holder (7', 7") for receiving the NMR sample at a loading position (5) and for transferring the NMR sample into the measuring volume at a transfer position (6), is characterized in that the sample holder for receiving the NMR sample is open upwards, that the cylindrical axis of the cylindrical sample holder of the sample changer is inclined at the loading position by an angle of inclination α between 30 and 60 degrees to the vertical, while it is vertical at the transfer position, and that a positioning device is provided.which transfers the NMR sample at the transfer position or after passing through it to the measurement position in the measurement volume with the sample axis of the NMR sample vertically aligned. This enables a more ergonomically efficient sample feed to the NMR spectrometer.