Indium Semiconductor Bio-sensing Device for Rapid Disease Diagnosis
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Solution Overview
Problem
Conventional bio-sensing methods for disease diagnosis are complex, require skilled personnel, and involve expensive, large apparatus that takes a long time to analyze samples.
Innovation Solution
A bio-sensing device with an electrode structure using an indium-containing semiconductor sensing film, a source and drain electrode, and a gate electrode, capable of varying electrical resistance in response to a target analyte, along with a surface filter membrane and receptor for efficient analyte detection.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If conventional immunoassay methods are used, then measurement precision can be achieved, but device complexity and cost increase significantly
Solution Approach 1:
The patent replaces complex optical measurement systems with a simple electrical resistance measurement system. The sensing film's electrical resistance changes in response to analyte binding, eliminating the need for complex optical equipment while maintaining measurement precision through the FET device's electrical detection capability.
Solution Approach 2:
The patent extracts and isolates the essential sensing function into a minimal FET device structure with source electrode, drain electrode, gate electrode, and sensing film. This extraction removes unnecessary complex components from conventional immunoassay systems while preserving the core measurement capability.
2Measurement precision
If conventional immunoassay methods are used, then measurement precision can be achieved, but analysis time increases
Solution Approach 1:
The electrical resistance-based detection method enables faster signal generation and readout compared to optical methods. The FET device responds rapidly to analyte binding events, reducing the time required to obtain diagnostic results while maintaining measurement precision.
3Measurement precision
If conventional immunoassay methods are used, then measurement precision can be achieved, but ease of operation deteriorates
Solution Approach 1:
Electrical resistance measurements are inherently simpler to perform and interpret than optical measurements. The FET device provides direct electrical readout that requires minimal technical expertise, making the diagnostic system easier to operate while maintaining measurement precision.
4Measurement precision
If conventional immunoassay methods are used, then measurement precision can be achieved, but cost increases
Solution Approach 1:
The FET-based sensing system uses simple electrical components that are cheaper to manufacture than complex optical systems. The sensing film can be deposited using standard thin-film techniques, and the overall device structure requires fewer expensive materials and components, reducing manufacturing costs while maintaining measurement precision.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The bio-sensing device maximizes sensing film performance, significantly shortens analysis time, and simplifies the analysis process, making it more accessible and cost-effective for disease diagnosis.
Implementation Method 1
a sensing film, which is a channel between the source electrode and the drain electrode, and that can vary in electrical resistance by a target analyte
Data Source
AI summary
The present invention provides a bio-sensing device comprising: a source electrode and a drain electrode which are arranged to be spaced apart from each other; a sensing film, which is a channel between the source electrode and the drain electrode and has an electrical resistance value that can be changed by a target analyte; and a gate electrode arranged to be spaced apart from the sensing film, wherein the sensing film is formed from a semiconductor including an indium (In) element.