Individualized Tablet Press with Dynamic Dosing Control
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Solution Overview
Problem
Existing methods for producing tablets are limited by the need for standardized doses, which can lead to doses that are too high for individual patients, resulting in unnecessary strain on the patient's organ system and waste of pharmaceutical materials.
Innovation Solution
A method and apparatus for automatically producing individualized tablets with a specifiable quantity of active substance using a compact tablet press, which allows for inputting a target number and mass of the active substance, controlling a dosing device, upper and lower punches, and transferring the tablets into a container.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Productivity
If standardized doses are used to meet the great need for tablets, then productivity is improved, but dosing precision for individual patients deteriorates
Solution Approach 1:
The patent implements a dynamically adjustable dosing system where the die cavity volume can be modified to accommodate different target masses of active substance. The system allows real-time adjustment of pressing parameters and die configurations to achieve precise individualized dosing while maintaining efficient production capabilities.
Solution Approach 2:
The patent changes key parameters including die cavity volume, active substance mass, and pressing force to enable production of tablets with individually tailored dosages. The system adjusts these parameters based on patient-specific requirements while maintaining standardized production processes.
2Productivity
If standardized tablet packages are used, then productivity is improved, but loss of substance deteriorates
Solution Approach 1:
The patent applies local quality by customizing the dosage quantity within each tablet package according to the specific patient's needs. Instead of uniform standardized packages, the system creates locally tailored packages with precise dosage amounts, reducing waste while maintaining production efficiency.
Solution Approach 2:
The system changes the quantity parameter of active substance per tablet based on individual patient requirements. The control system adjusts the mass of active substance filled into each tablet, enabling precise customization that minimizes pharmaceutical material waste while maintaining efficient production.
3Reliability
If doses that are too high are selected to ensure treatment effect, then reliability of treatment is improved, but object-affected harmful factors deteriorate
Solution Approach 1:
The patent changes the dosage parameter to match the individual patient's specific requirements. The control system calculates and adjusts the exact mass of active substance needed based on patient characteristics, ensuring sufficient treatment effect while avoiding excessive dosing that would strain the organ system.
Solution Approach 2:
The system incorporates feedback mechanisms where patient data is input into the control system, which then calculates the appropriate dosage. This feedback loop ensures that the dosage is precisely tailored to each patient's needs, maintaining treatment effectiveness while minimizing harmful effects.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This solution enables the production of tablets with exact dosages tailored to individual patients, reducing the risk of overdosing and waste, while allowing for decentralized production in medical settings such as doctor's offices or pharmacies.
Implementation Method 1
a pressure face of the lower punch, the outer circumference of which corresponds to an inner circumference of the central opening, closes the central opening from below
Implementation Method 2
pressing the first active substance by vertically extending a pressure face of the upper punch, the outer circumference of which corresponds to the inner circumference of the central opening, into the central opening from above
Implementation Method 3
transferring the pressed tablet into the tablet container by means of the transfer device
Data Source
AI summary
A tablet press for producing tablets including: a press chamber, a receiving chamber, a first material container having the first active substance with a first dosing device, a controller, and an input device. The press chamber has an extendable upper punch, an extendable lower punch, and a die. The input device inputs a target indicating a number of produced tablets and a target mass indicating a quantity of the first active substance and transmits the target number and the target mass to the controller. The controller actuates the first dosing device, the upper punch, and the lower punch such that a quantity of the first active substance that corresponds to the target mass is filled into a central opening of the die and pressed by the punches to form a tablet, and to repeat until the target number of tablets are produced.