Individualized TMS Target Frequency Determination via EEG Analysis
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Solution Overview
Problem
Current methods for diagnosing and treating mental disorders rely heavily on subjective interviews and lack objective, measurable data, leading to potential biases and inaccuracies in diagnosis and treatment.
Innovation Solution
The use of EEG measurements to determine a target frequency for individualized transcranial magnetic stimulation (TMS) treatments, aligning brain activity across multiple brain zones to promote optimal brain function and address various mental disorders.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If subjective interviews are used for diagnosing mental disorders, then the diagnostic process is simple and quick, but the accuracy and objectivity of diagnosis deteriorates due to interviewer and subject bias
Solution Approach 1:
The patent replaces the mechanical/manual interview-based diagnostic system with an automated EEG-based diagnostic system. The processor automatically analyzes EEG signals to determine brain frequency alignment, substituting the subjective human interview process with objective physiological measurement and automated analysis, thereby eliminating interviewer and subject bias while improving diagnostic accuracy.
2Reliability
If standardized TMS protocols are used for treatment, then the treatment process is simple and consistent, but the effectiveness deteriorates due to lack of individualization for each patient's specific brain frequency
Solution Approach 1:
The patent applies local quality by customizing the TMS treatment frequency to match each patient's specific target frequency determined from their individual EEG analysis. Instead of using a standardized frequency for all patients, the system adjusts the TMS frequency locally to each patient's optimal brain wave frequency, thereby improving treatment effectiveness while maintaining protocol consistency through automated determination.
Solution Approach 2:
The patent implements preliminary action by performing EEG analysis and determining the target frequency before administering TMS treatment. This preliminary assessment allows the treatment protocol to be individually customized based on each patient's specific brain frequency characteristics, ensuring that the subsequent TMS treatment is optimally tailored to their needs.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This approach provides an objective and effective method for diagnosing and treating mental disorders by aligning brain frequencies, improving mental wellness and reducing symptoms across a range of conditions including depression, anxiety, and ADHD.
Implementation Method 1
causing a TMS system to provide the one or more treatments to the subject in accordance with the treatment protocol. The treatment protocol may include one or more individualized transcranial magnetic stimulation (TMS) treatments that each include application a plurality of magnetic stimulation pulses
Data Source
AI summary
Systems and methods for treatment of a mental disorder of a subject are disclosed. The methods include receiving a first set of electroencephalography (“EEG”) measurements that each correspond to brain activity at one or more of a plurality of zones of a brain of the subject. The methods further include determining a target frequency for the subject based on the first set of EEG measurement where, the target frequency being an EEG frequency where the brain of the subject operates optimally across a plurality of EEG channels in an alpha brainwave, and generating a treatment protocol for the subject based on the target frequency. The treatment protocol includes one or more individualized transcranial magnetic stimulation (TMS) treatments that each include application a plurality of magnetic stimulation pulses for a defined time period and at a frequency of about the target frequency.


