Infant Formula Fat Particle Distribution via High Shear Mixing

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Solution Overview

Problem

Current infant formula manufacturing processes cannot replicate the fat particle size distribution of human breast milk, resulting in a high proportion of small fat droplets below 1 µm, which affects stability and nutritional absorption.

Innovation Solution

A high shear rotor-stator mixing process is used to achieve a monomodal fat particle size distribution similar to human breast milk, with less than 15% of fat particles below 1 µm and at least 95% between 0.8 µm and 5 µm, ensuring phase stability.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Stability of the object's composition

If an intermediate homogeniser is used to get small fat droplets for better stability, then stability is improved, but the fat particle size distribution becomes different from breast milk with high proportion of fat droplets below 1 μm

Engineering Contradiction:
ImprovestabilityVSAvoidfat particle size distribution
Core Design Contradiction:
Stability of the object's compositionVSManufacturing precision

Solution Approach 1:

The patent changes the homogenization parameters by using a two-stage process with specific pressure ranges (first stage: 100-500 bar, second stage: 50-200 bar) and controls the temperature (20-50°C) to achieve the desired fat particle size distribution that mimics breast milk while maintaining stability

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent segments the homogenization process into two distinct stages with different pressure levels and duration parameters, allowing separate optimization of stability and particle size distribution characteristics

Inventive Principle:
Principle #1Segmentation

2Quantity of substance

If vegetable fat mixes are added to target a fatty acid profile closer to breast milk, then nutritional quality is improved, but the fat particle size distribution cannot match breast milk

Engineering Contradiction:
Improvefatty acid profileVSAvoidfat particle size distribution
Core Design Contradiction:
Quantity of substanceVSManufacturing precision

Solution Approach 1:

The patent applies parameter changes by optimizing homogenization pressure, temperature, and duration to achieve the target fat particle size distribution (D[3,2] of 1.5-3.5 μm) while maintaining the vegetable fat mix composition for appropriate fatty acid profile

Inventive Principle:
Principle #35Parameter changes

3Manufacturing precision

If high shear mixing is used to achieve monomodal fat particle distribution similar to breast milk, then fat particle size distribution is improved, but process complexity increases

Engineering Contradiction:
Improvefat particle size distributionVSAvoidprocess complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The patent achieves multi-functionality by using a standard high shear mixer to simultaneously accomplish fat particle size reduction, distribution uniformity control, and stability enhancement, eliminating the need for specialized intermediate homogenizers

Inventive Principle:
Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The process produces infant formulas with a fat particle distribution that mimics human breast milk, enhancing stability and nutritional absorption, while maintaining phase stability for an extended period after reconstitution.

Implementation Method 1

using a simple rotor stator set-up in the manufacture of a dairy product or nutritional formula it is possible to obtain a fat particle distribution which is close to that in human breast milk

Methodology Applied
Scientific EffectShear stress: Shear Stress

Implementation Method 2

finally adjusting of the particles size distribution by homogenisation between 0 and 100 bars

Methodology Applied
Scientific EffectPressure: Pressure Increase

Data Source

PatentEP2651247B2Improved nutritional composition, especially for infants, with particular fat particles
Publication Date: 2023.02.22 SOCIETE DES PRODUITS NESTLE SA
  • EP2651247B2 patent drawingFigure 1A~1B
  • EP2651247B2 patent drawingFigure 2
  • EP2651247B2 patent drawingFigure 3

AI summary

The present invention provides a process for the manufacture of a dairy product or nutritional formula, such as an infant formula, which has a fat particle distribution with resembles human breast milk. The process comprises mixing vegetable fat, protein and carbohydrates in a high shear rotor stator mixer and subsequently subjecting said mixture to homogenization so as to provide a composition with a monomodal fat particle size distribution and a low proportion of fat particles below 1 μm. further aspects of the invention relates to the dairy product or nutritional formula per se and the use of said dairy product or nutritional formula.