Inhaler Ratio Control via Heating and Airflow Profiles

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Solution Overview

Problem

Current technologies for pulmonary delivery of active substances, particularly cannabinoids, struggle to provide a controlled ratio of multiple active substances from the same source material during a single inhalation.

Innovation Solution

An inhaler system that defines and delivers a controllable ratio of at least two active substances, such as cannabinoids and their acidic forms, by setting operation parameters including heating profiles and airflow profiles, allowing for simultaneous or sequential delivery during a single inhalation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Manufacturing precision

If conventional inhaler technologies are used to deliver active substances, then the delivery process is simple, but the ability to control the ratio of multiple active substances is poor

Engineering Contradiction:

Improvecontrol precision of active substance ratioVSAvoidcomplexity of inhaler system

Core Design Contradiction:

Manufacturing precisionVSDevice complexity

Solution Approach 1:

The inhaler employs dynamic control of heating parameters (temperature, heating rate, heating duration) and airflow parameters to dynamically adjust the release ratio of multiple active substances from the same source material during a single inhalation, enabling precise ratio control without requiring multiple separate delivery mechanisms

Inventive Principle:

Principle #15Dynamics

Solution Approach 2:

The system changes operational parameters including heating profile (temperature, rate, duration) and airflow profile to control the chemical and physical release characteristics of active substances, thereby controlling the ratio of substances delivered while using a single inhalation event

Inventive Principle:

Principle #35Parameter changes

2Reliability

If multiple active substances are delivered from the same source material, then the therapeutic effectiveness is improved, but the difficulty of controlling the delivery ratio increases

Engineering Contradiction:

Improvetherapeutic effectivenessVSAvoiddifficulty of controlling delivery ratio

Core Design Contradiction:

ReliabilityVSDifficulty of detecting and measuring

Solution Approach 1:

The inhaler incorporates sensors to detect parameters such as temperature, airflow rate, and substance release characteristics in real-time, using this feedback to dynamically adjust heating and airflow parameters to maintain the desired ratio of multiple active substances during delivery

Inventive Principle:

Principle #23Feedback

Solution Approach 2:

The system replaces complex mechanical mixing or separate delivery mechanisms with controlled thermal and airflow fields to manage the release of multiple active substances, using physical and chemical processes rather than mechanical separation to achieve ratio control

Inventive Principle:

Principle #28Mechanics substitution (Replace mechanical system)

3Ease of operation

If a single inhalation is used to deliver multiple substances, then the user convenience is improved, but the control over the ratio of substances delivered becomes more difficult

Engineering Contradiction:

Improveuser convenienceVSAvoidcontrol precision of substance ratio

Core Design Contradiction:

Ease of operationVSManufacturing precision

Solution Approach 1:

The inhaler pre-configures heating profiles and airflow parameters before the inhalation event, establishing controlled conditions in advance that enable precise ratio control of multiple active substances to be delivered simultaneously in a single inhalation without requiring complex real-time adjustments

Inventive Principle:

Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables precise control over the ratio of active substances delivered, potentially enhancing therapeutic effects while minimizing adverse reactions, and allows for flexible operation profiles to achieve desired therapeutic outcomes.

Implementation Method 1

applying a selected operation profile to a source material... the operation profile comprises at least one of: a temperature-time profile and an airflow-time profile

Methodology Applied

Scientific EffectHeating: Heating

Implementation Method 2

an airflow system for passing airflow through the source material and for delivering at least two active substances released from the source material to an inhaling user

Methodology Applied

Scientific EffectConvection: Convection

Data Source

PatentUS20250151812A1Method and inhaler for providing two or more substances by inhalation

Publication Date: 2025.05.15 SYQE MEDICAL LTD

AI summary

A method for providing, during a single inhalation from an inhaler, a first active substance and a second active substance from one source material is disclosed. The method includes defining a ratio of the first and second active substances to be delivered to a user; setting operation parameters in accordance with the ratio, the operation parameters including one or both of a heating profile of the source material and an airflow profile through the source material; and operating the inhaler according to the operation parameters to deliver to the user, during a single inhalation, at least the first and second active substances at the defined ratio.