Inhaler Heating Element Vaporization Control

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Solution Overview

Problem

Inhalation devices often deliver uncontrolled and inconsistent dosages of pharmaceuticals, raising regulatory issues and posing challenges in rapid and precise delivery of drugs to the lung and brain for conditions such as pain, anxiety, and seizures.

Innovation Solution

A portable inhalation device with a disposable cartridge containing a pharmaceutical-coated heating element and a reusable controller, which heats the pharmaceutical to vaporize it for controlled inhalation, utilizing a breath sensor to activate heating and ensuring consistent dosing through precise temperature control and pulse width modulation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Speed

If conventional inhalation devices are used to deliver pharmaceuticals rapidly, then the speed of drug delivery to the brain is improved, but the dosage control becomes uncontrolled and inconsistent

Engineering Contradiction:
Improvespeed of drug deliveryVSAvoiddosage control precision
Core Design Contradiction:
SpeedVSManufacturing precision

Solution Approach 1:

The patent employs pulse width modulation (PWM) to dynamically control the heating element's power delivery, adjusting the duty cycle to maintain precise temperature control during vaporization. This parameter change approach allows rapid heating while maintaining consistent dosing by modulating energy input in real-time based on temperature feedback

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The system incorporates temperature sensors that continuously monitor the heating element temperature and feed this information back to the control circuit. The feedback loop adjusts the PWM signal to maintain the heating element within a precise temperature range, ensuring consistent pharmaceutical vaporization and dosage control while enabling rapid delivery

Inventive Principle:
Principle #23Feedback

2Speed

If the heating element resistance is reduced to enable rapid heating, then the speed of vaporization is improved, but the energy efficiency decreases

Engineering Contradiction:
Improveheating speedVSAvoidenergy efficiency
Core Design Contradiction:
SpeedVSUse of energy by moving object

Solution Approach 1:

The system uses periodic pulsed heating through PWM control, delivering energy in controlled bursts rather than continuous operation. This periodic action allows the heating element to rapidly heat during pulse intervals while dissipating excess heat during off-intervals, achieving fast vaporization while maintaining energy efficiency by avoiding continuous high-power consumption

Inventive Principle:
Principle #19Periodic action

Solution Approach 2:

The heating system transitions from static resistance to dynamic resistance control through PWM modulation. The effective resistance changes dynamically during operation, allowing the system to optimize between rapid heating (lower effective resistance during pulses) and energy efficiency (higher effective resistance during intervals), adapting to real-time temperature requirements

Inventive Principle:
Principle #15Dynamics

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The device provides rapid, controlled, and consistent delivery of pharmaceuticals, addressing regulatory concerns by ensuring precise dosing and minimizing misuse through lockout features and antagonist integration, enhancing treatment efficacy for conditions like pain and anxiety.

Implementation Method 1

a heating element having a resistance of 0.2-3 Ohm, wherein the heating element is configured to heat the first pharmaceutical, wherein the heating element is configured to be heated by passage of an electrical current

Methodology Applied
Scientific EffectJoule heating: Joule Heating

Implementation Method 2

the cartridge is configured to pass a vapor of the first pharmaceutical to the airflow pathway

Methodology Applied
Scientific EffectVaporization: Evaporation

Data Source

PatentEP3909628B1Devices for controlled drug vaporization
Publication Date: 2024.07.03 THE TRUSTEES OF PRINCETON UNIV
  • EP3909628B1 patent drawingFigure 1
  • EP3909628B1 patent drawingFigure 2
  • EP3909628B1 patent drawingFigure 3

AI summary

The present invention an electronic inhaler for the delivery of pharmaceuticals through vaporization.