Inhaler Resistance Measurement Closed-Loop System

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Solution Overview

Problem

Existing methods for measuring the resistance of inhalers to airflow are cumbersome, involve multiple steps, and are susceptible to variations in ambient conditions, making them inefficient and prone to errors.

Innovation Solution

A closed-loop system comprising a pressure controller, flow controller, microprocessors, and sensors that measure pressure differential and flow rate across an inhaler in a controlled environment, using a sealed airflow pathway to determine resistance values with high accuracy and ease of use.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If existing methods for measuring inhaler resistance are used, then the measurement process can be completed, but the process is cumbersome and involves multiple steps

Engineering Contradiction:
Improvemeasurement speedVSAvoidnumber of steps
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent combines multiple measurement functions into a single integrated apparatus. The flow generator, pressure transducers, flow meter, and computer are merged into one system that performs all necessary measurements simultaneously in a single test setup, eliminating the need for multiple separate steps and procedures

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The apparatus is designed as a universal measurement system that can test different inhaler types and configurations using the same equipment. The system performs multiple functions including flow rate measurement, pressure differential measurement, and resistance calculation all through one integrated platform

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Measurement precision

If existing measurement methods are used, then resistance can be measured, but the results are subject to variations in ambient conditions

Engineering Contradiction:
Improveresistance measurement accuracyVSAvoidambient condition variations
Core Design Contradiction:
Measurement precisionVSObject-affected harmful factors

Solution Approach 1:

The patent creates a controlled test environment that isolates the inhaler from ambient air conditions. The system uses a closed circuit with controlled atmosphere where the inhaler is tested under standardized conditions, eliminating the influence of external temperature, pressure, and humidity variations

Inventive Principle:
Principle #39Inert atmosphere (Inert environment)

Solution Approach 2:

The system continuously monitors pressure differentials and flow rates using transducers and provides real-time feedback to the computer, which automatically adjusts and compensates for any variations, ensuring consistent and accurate resistance measurements regardless of external conditions

Inventive Principle:
Principle #23Feedback

3Productivity

If existing methods are used, then measurements can be obtained, but they require numerous steps and calculations

Engineering Contradiction:
Improvemeasurement efficiencyVSAvoidnumber of calculations
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent replaces manual calculations and mechanical measurement procedures with automated electronic systems. The computer automatically processes data from pressure transducers and flow meters, performing resistance calculations electronically without requiring manual intervention or complex computational steps

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system provides rapid, accurate, and reproducible measurements of inhaler resistance, eliminating environmental variables and reducing errors, while being adaptable to different inhaler designs and materials.

Implementation Method 1

a pressure sensor configured to measure pressure differential across an inhaler

Methodology Applied
Scientific EffectPressure differential measurement: Pressure Gradient

Implementation Method 2

a laminar flow sensor configured to measure the flow rate of airflow within the chamber

Methodology Applied
Scientific EffectLaminar flow measurement: Laminar Flow

Implementation Method 3

a vacuum pump; a flow controller or flow regulator which is configured to connect to a positive air pressure generator

Methodology Applied
Scientific EffectVacuum suction: Vacuum

Implementation Method 4

a flow controller or flow regulator which is configured to connect to a positive air pressure generator

Methodology Applied
Scientific EffectPressure-driven flow: Pressure Gradient

Data Source

PatentUS9983108B2Apparatus, system and method for measuring resistance of an inhaler
Publication Date: 2018.05.29 MANNKIND CORP
  • US9983108B2 patent drawing
  • US9983108B2 patent drawing
  • US9983108B2 patent drawing

AI summary

An apparatus, a closed-loop system and method for measuring the resistance of inhalation systems and/or devices are disclosed.