Injectable Liquid Composition for Facial Ligament Support

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Solution Overview

Problem

Current treatments for aging facial skin and structures, such as surgery, are invasive, painful, and unsightly, and there is a need for a minimally invasive method to address ligamentous laxity and improve facial contour and shape without significant side effects.

Innovation Solution

A liquid composition comprising water, osmotic agents (500-5000 mOsm), high viscosity components (10-1500 mPas), micro-particles (0.001-0.25 mm), and optionally local anesthetics, administered via injection near or into facial ligaments to improve ligamentous laxity and facial appearance.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Shape

If surgery is used to treat ageing facial skin and structures, then the facial contour and shape can be improved, but the treatment becomes invasive, painful, and unsightly

Engineering Contradiction:
Improvefacial contour and shapeVSAvoidinvasiveness and pain
Core Design Contradiction:
ShapeVSObject-affected harmful factors

Solution Approach 1:

The patent replaces surgical mechanical intervention with a chemical injection treatment. The composition containing osmotic agents, viscosity increasing substances, and micro-particles is injected into the facial ligaments to stimulate collagen production and improve facial contour without the invasiveness and pain of surgery

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent changes the physical and chemical parameters of the treatment by using compositions with specific osmotic concentrations (500-5000 mOsm), viscosity (10-1500 mPas), and micro-particle sizes (0.001-0.25 mm) to achieve ligamentous tightening through biochemical mechanisms rather than mechanical surgery

Inventive Principle:
Principle #35Parameter changes

2Shape

If traditional treatments are used to address ligamentous laxity, then the facial appearance can be improved, but significant side effects occur

Engineering Contradiction:
Improvefacial appearanceVSAvoidside effects
Core Design Contradiction:
ShapeVSObject-generated harmful factors

Solution Approach 1:

The patent applies local quality by injecting the composition specifically into the facial ligaments rather than using broad systemic treatments. The composition contains localized proliferating agents and micro-particles that stimulate collagen production only at the injection site, minimizing systemic side effects while improving facial appearance

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The patent uses biodegradable micro-particles and temporary viscosity increasing substances that are metabolized or absorbed by the body over time. These disposable-like components provide temporary structural support and collagen stimulation without long-term accumulation or chronic side effects

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composition effectively improves facial contour and shape by enhancing ligament support, reducing pain, and providing a non-invasive alternative to surgery with minimal side effects, as demonstrated by increased collagen density and reduced pain in animal and potential human trials.

Implementation Method 1

a component A, which leads to an osmotic concentration in the range from 500 to 5000 mOsm

Methodology Applied
Scientific EffectOsmosis: Osmosis

Implementation Method 2

a high viscosity component B, which leads to a viscosity of the liquid composition in the range from 10 to 1500 mPas

Methodology Applied
Scientific EffectViscosity:

Data Source

PatentUS20230277432A1Composition for improving the appearance of ageing skin
Publication Date: 2023.09.07 MERZ PHARMA GMBH & CO KGAA
  • US20230277432A1 patent drawing

AI summary

A liquid composition for improving the facial contour and shape of the human or animal face by injection, the liquid composition comprising water and at least one of the following components A, B and C:at least one component A, which leads to an osmotic concentration in the range from 500 to 5000 mOsm in the liquid composition,at least one high viscosity component B, which leads to a viscosity of the liquid composition in the range from 10 to 1500 mPas,at least one micro-particles component C, comprising micro-particles with an average particle size not larger than 0.25 mm, preferably in the range of 0.001 mm to 0.25 mm, and optionally comprisinga local anesthetic compound D.