Injectable Wire Electrode Structure for Stable Tissue Integration

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Existing electrodes for transmitting energy within the body face challenges such as dispersion of particles leading to reduced efficacy and difficulty in full removal, along with systemic side effects and traumatic implantation procedures.

Innovation Solution

An injectable wire structure electrode designed to be highly conductive and mechanically strong, composed of ultra-thin wires compacted into a small volume for minimally invasive placement, with a roughened and porous surface to enhance biocompatibility and charge injection capacity.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If micron-sized conductive particles are mixed into a flowable curable glue for minimally invasive injection, then the electrode can be injected through a needle, but the particles can dissipate or be moved after immune defenses and fibrous tissue intervene, reducing efficacy

Engineering Contradiction:
ImproveinjectabilityVSAvoidefficacy maintenance
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The electrode is segmented into ultra-thin wire sections that are compacted together, allowing the segmented structure to be injected through a needle while maintaining structural integrity. The segmentation enables flexibility for injection while preserving the continuous conductive pathway for reliable energy transmission.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The electrode combines ultra-thin highly conductive wire material with a compacted structured configuration, creating a composite structure that integrates the mechanical properties needed for injection with the electrical properties needed for reliable energy transmission, preventing particle dispersion issues.

Inventive Principle:
Principle #40Composite materials

2Reliability

If traditional implantable electrodes are used, then they can provide stable energy transmission, but the implantation surgery through open cut downs is traumatic and expensive

Engineering Contradiction:
Improveenergy transmission stabilityVSAvoidsurgical trauma
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The electrode uses ultra-thin wire structures that can be flexed and compacted into a small volume for injection through a needle, eliminating the need for traumatic open cut down surgery while maintaining the stability and reliability of energy transmission associated with traditional implantable electrodes.

Inventive Principle:
Principle #30Flexible shells and thin films

3Strength

If rigid electrodes are used to maintain mechanical strength, then structural integrity is achieved, but tissue irritation increases and fibrotic encapsulation worsens

Engineering Contradiction:
Improvemechanical strengthVSAvoidtissue irritation
Core Design Contradiction:
StrengthVSObject-affected harmful factors

Solution Approach 1:

The electrode parameters are changed by using ultra-thin wire dimensions and compacted configurations that reduce mechanical rigidity to minimize tissue irritation and fibrotic encapsulation, while the material selection and structural design maintain sufficient mechanical strength for stable energy transmission.

Inventive Principle:
Principle #35Parameter changes

4Reliability

If highly conductive materials are used to transmit energy efficiently, then charge injection capacity increases, but the wire diameter increases reducing flexibility

Engineering Contradiction:
Improvecharge injection capacityVSAvoidflexibility
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The electrode transitions from a traditional solid rod geometry to a compacted structured configuration of ultra-thin wires, changing the dimensional arrangement to achieve high charge injection capacity through increased surface area while maintaining flexibility through the thin wire construction and compacted structure.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The injectable wire structure electrode achieves high conductivity and mechanical strength, maintaining efficacy over extended periods with minimal systemic side effects and easy removal, while promoting biocompatibility and tissue integration.

Implementation Method 1

transmit energy within the body at a higher conductivity for this energy than for surrounding tissues

Methodology Applied
Scientific EffectElectrical conduction: Conduction (electrical)

Implementation Method 2

overlapping loops create a highly conductive pathway for transmission of energy

Methodology Applied
Scientific EffectElectrical conduction: Conduction (electrical)

Data Source

PatentUS12285601B2Ex vivo method of manufacturing a wire structure electrode
Publication Date: 2025.04.29 NEURONOFF INC
  • US12285601B2 patent drawing
  • US12285601B2 patent drawing
  • US12285601B2 patent drawing

AI summary

An injectable wire structure electrode can assimilate with surrounding tissues after injection, inducing in-growth of blood vessels, collagen and other tissue. Assimilation secures the electrode to the tissue without sutures and prevents relative motion which can lead to inflammation and scarring. Associated methods of manufacturing and injection are disclosed, as well as systems including a dermal multiplexer for power delivery.