Injection Assembly Sensing for Orientation and Skin Contact Verification

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Solution Overview

Problem

Existing medication delivery devices lack comprehensive status sensing systems to ensure proper operation, orientation, temperature management, and skin contact verification, which can compromise the effectiveness and safety of medication administration.

Innovation Solution

Integration of sensing systems within or as modules in medication delivery devices to track component location and movement, orientation, temperature, and skin contact, utilizing sensors like accelerometers, magnetic field sensors, temperature sensors, and skin contact sensors, with communication to external devices for user feedback.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If comprehensive sensing systems are integrated into medication delivery devices to monitor orientation, temperature, component location, and skin contact, then the reliability and safety of medication delivery are improved, but the device complexity increases

Engineering Contradiction:
Improvemedication delivery reliabilityVSAvoiddevice complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The sensing system is divided into multiple independent sensor modules, each responsible for detecting specific parameters (orientation, temperature, component location, skin contact). This segmentation allows the complex monitoring function to be broken down into manageable, specialized sensor units that can be independently optimized and maintained.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The sensing system is designed to perform multiple functions simultaneously using a integrated set of sensors that monitor orientation, temperature, component location, and skin contact. This multi-functional approach consolidates what could be separate systems into a unified sensing platform, reducing overall system complexity while maintaining comprehensive monitoring capabilities.

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Measurement precision

If multiple sensors are integrated to track component location and movement, then the measurement precision of device status is improved, but the device complexity increases

Engineering Contradiction:
Improvecomponent location measurement precisionVSAvoiddevice complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

Multiple sensors that detect component location and movement are merged into an integrated sensing system with a unified processing architecture. This consolidation allows the system to achieve high measurement precision through coordinated sensor input while avoiding the complexity of managing entirely separate detection systems.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent replaces complex mechanical position indication mechanisms with electronic sensing systems. Instead of relying on mechanical linkages or visual indicators to show component location, the system uses electronic sensors to detect and report status, simplifying the mechanical structure while improving measurement precision.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Reliability

If sensing systems with multiple sensors are integrated into the device, then the safety and proper operation verification are improved, but the manufacturing complexity increases

Engineering Contradiction:
Improveproper operation verificationVSAvoidmanufacturing complexity
Core Design Contradiction:
ReliabilityVSEase of manufacture

Solution Approach 1:

The sensing system is designed to perform preliminary verification of proper operation before medication delivery occurs. Sensors check orientation, temperature, component location, and skin contact in advance, allowing the system to confirm correct setup and prevent improper administration before it happens, thereby improving safety without requiring complex post-delivery verification mechanisms.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enhances the reliability and safety of medication delivery by ensuring proper device orientation, temperature compliance, and accurate skin contact, reducing the risk of improper use and ensuring complete dose administration.

Implementation Method 1

an accelerometer configured to detect a shock associated with the drive mechanism driving the syringe assembly from the storage position to the injection position

Methodology Applied
Scientific EffectAccelerometer: Accelerometer

Implementation Method 2

a magnetometer configured to detect a position of the syringe assembly

Methodology Applied
Scientific EffectMagnetic field detection: Magnetometer

Implementation Method 3

temperature sensors

Methodology Applied
Scientific EffectTemperature sensing: Thermistor

Data Source

PatentEP4059548B1Status sensing systems within an injection device assembly
Publication Date: 2026.03.18 ELI LILLY & CO
  • EP4059548B1 patent drawingFigure 1
  • EP4059548B1 patent drawingFigure 2
  • EP4059548B1 patent drawingFigure 3

AI summary

An injection device assembly including a housing, a syringe, a drive mechanism and one or more sensing systems are described. The drive mechanism advances the syringe from a storage position to an injection position, and a plunger advances the syringe piston from an initial position to a final position. The status sensing system may include one or more main PCB(s) disposed in an end portion of the injection device assembly's housing. The system may determine various parameters related to an operational status of the injection device, including the location of the device's components, an amount of medication remaining in the device, a temperature of the medication, and whether or not the device is properly contacting the user's skin before injection. The system may communicate such determined parameters to an external device via a wireless communication link.