Injection Device Dose Adjuster Mechanism

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Solution Overview

Problem

Existing fixed dose injection devices do not allow for adjustable medicament doses, which can cause discomfort or intolerance in patients, particularly those with chronic conditions like diabetes, as they are limited to a single predefined dose size.

Innovation Solution

An injection device with a dose size adjuster mechanism that allows users to modify the length of the rod assembly, enabling either a reduction or increase in the dose size by displacing the rod extension relative to the piston rod, thereby varying the dose dispensed.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If a fixed dose injection device is used, then the device structure is simple and easy to operate, but the dose size cannot be adjusted causing discomfort or intolerance in patients

Engineering Contradiction:
Improvedose size adjustabilityVSAvoiddevice structure complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent applies the dynamics principle by making the rod extension movable relative to the piston rod through the adjuster mechanism. This allows the dose size to be dynamically adjusted by displacing the rod extension, transforming the fixed dose device into an adjustable dose device while maintaining relative structural simplicity

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The patent segments the rod assembly into the piston rod and the movable rod extension. This segmentation allows the dose adjustment function to be isolated in the rod extension component, enabling independent adjustment of dose size without complicating the entire device structure

Inventive Principle:
Principle #1Segmentation

2Adaptability or versatility

If the rod extension is made movable to allow dose adjustment, then dose size can be varied, but the device complexity increases

Engineering Contradiction:
Improvedose modification capabilityVSAvoidadjuster mechanism complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The adjuster acts as an intermediary mechanism between the user and the rod extension. It provides a simple interface (adjustment element) that translates user input into controlled displacement of the rod extension, enabling dose adjustment without requiring complex control systems

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The adjuster mechanism is designed to be self-contained and operable by the user without requiring external assistance or complex control systems. The mechanism allows patients to independently adjust their dose size through simple manipulation of the adjustment element

Inventive Principle:
Principle #25Self-service

Data Source

PatentUS11865318B2Injection device with dose size adjuster
Publication Date: 2024.01.09 SANOFI SA(FR)
  • US11865318B2 patent drawing
  • US11865318B2 patent drawing
  • US11865318B2 patent drawing

AI summary

The present disclosure relates to an injection device configured to expel a dose of a medicament, the injection device comprising: an elongated housing extending in a longitudinal direction, a piston rod movable relative to the housing in a longitudinal distal direction to exert a dispensing pressure onto a bung of a cartridge at least partially filled with an injectable medicament, a rod extension movably arranged on or in a distal end of the piston rod, a driver operably engaged with the piston rod and movable relative to the housing in a longitudinal proximal direction for setting of the dose and movable relative to the housing in the longitudinal distal direction for dispensing of the dose, and an adjuster arranged on or in the driver and operably engaged with the rod extension to move the rod extension in longitudinal direction relative to the piston rod.