Injection Device Stopping Member for Microinjection Precision

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Solution Overview

Problem

Ordinary syringes in the prior art cannot meet the requirements of microinjection due to excessive errors in dose measurement, especially for microinjections of 50, 100, or 200 microliters, where the error needs to be within ±10% or ±5 microliters.

Innovation Solution

An injection device is provided that does not change the original structure of a syringe, featuring a barrel with a flange and a push rod connected with a stopping member. The stopping member has a first stopping portion and a second stopping portion at different positions, allowing for precise control of the injection dose by determining the fixed distance between these portions.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If conventional syringes with graduation marks are used for microinjection, then the device structure remains simple and cost-effective, but the measurement precision of injection dose cannot meet the requirements (error exceeds ±10%)

Engineering Contradiction:
Improveinjection dose precisionVSAvoiddevice structure complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

A stopping member is introduced as an intermediary component between the push rod and the user's finger. This stopping member features a first stopping surface and a second stopping surface at a fixed distance apart, which limits the push rod's travel distance. By using this mechanical intermediary, the syringe achieves precise microinjection (within ±10% error) without requiring complex electronic control systems, thereby resolving the contradiction between measurement precision and device complexity.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Adaptability or versatility

If multiple tolerance parameters (D, L1, L2, L3, L4) are involved in calculating injection dose, then the syringe can accommodate various dimensions, but the accumulation of tolerances increases the dose error to about 18%

Engineering Contradiction:
Improvesyringe dimension adaptabilityVSAvoidinjection dose precision
Core Design Contradiction:
Adaptability or versatilityVSMeasurement precision

Solution Approach 1:

The invention extracts and isolates the critical dimension parameter by fixing the distance between the first and second stopping surfaces of the stopping member. Instead of relying on multiple dimensional parameters (D, L1, L2, L3, L4) that accumulate tolerances, the dose is determined primarily by the single fixed distance parameter between stopping surfaces. This extraction of the key dimension reduces tolerance accumulation from five parameters to essentially one critical parameter, thereby improving dose precision while maintaining adaptability.

Inventive Principle:
Principle #2Taking out (Extraction)

3Measurement precision

If special microsyringes are used to achieve accurate microinjection, then the injection precision meets requirements, but the cost increases and ordinary syringes are not available

Engineering Contradiction:
Improvemicroinjection precisionVSAvoidmanufacturing cost
Core Design Contradiction:
Measurement precisionVSEase of manufacture

Solution Approach 1:

The stopping member is designed as a universal component that can be attached to ordinary syringes to transform them into precise microinjection devices. Rather than requiring specially manufactured microsyringes, the stopping member provides the precision function across different syringe types. This multi-functional approach allows ordinary syringes to achieve microinjection precision (within ±10% or ±5 microliters), thereby reducing manufacturing costs while maintaining high precision.

Inventive Principle:
Principle #6Universality (Multi-functionality)

4Productivity

If the push rod is pushed until the rubber stop contacts the bottom of the injection barrel, then the injection is completed, but the rubber stop deforms and squeezes out medication, increasing dose error to about 20% or more

Engineering Contradiction:
Improveinjection completion efficiencyVSAvoidinjection dose precision
Core Design Contradiction:
ProductivityVSMeasurement precision

Solution Approach 1:

The stopping surfaces on the stopping member perform a preliminary action by limiting the push rod's travel distance before the rubber stop reaches the bottom of the barrel. The first stopping surface prevents over-pushing, and the second stopping surface provides a reference point. This preliminary limitation of travel distance prevents rubber stop deformation and medication squeeze-out, maintaining dose precision within ±10% while ensuring complete injection through the controlled movement.

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS20250041520A1Injection device and method for using same
Publication Date: 2025.02.06 HANGZHOU QIANTANG LONGYUE BIOTECHNOLOGY CO LTD
  • US20250041520A1 patent drawing
  • US20250041520A1 patent drawing
  • US20250041520A1 patent drawing

AI summary

Provided are an injection device, an injection device without changing an original structure of a syringe, and a method for using the same. The injection device includes a barrel (1) with a flange (8) and a push rod (2) slidably connected in the barrel (1). One end of the push rod (2) is provided with a piston (3), and the other end is provided with a thumb rest (4). The push rod (2) or the barrel (1) is detachably connected with a stopping member (5), and the stopping member (5) is provided with a first stopping portion (51) and a second stopping portion (52) at different positions. A distance between the first stopping portion (51) and the second stopping portion (52) is a fixed distance. The push rod (2) is moved, and when the thumb rest (4) or the flange (8) abuts against the first stopping portion (51), the injection device is in an injection start position; and when the thumb rest (4) or the flange (8) abuts against the second stopping portion (52), the injection ends, and a gap is left between the piston (3) and the barrel (1). As long as the fixed distance between the first stopping portion and the second stopping portion is determined, the number of tolerances can be greatly reduced, thereby improving the injection accuracy. The piston (3) and a bottom of the barrel (1) do not squeeze each other, so that the piston will not deform. Therefore, a residual medication in a tapper cavity will not be squeezed out for injection, thereby improving the injection accuracy.