Large-Volume Injector Drive Assembly for Aseptic Force Transmission
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Solution Overview
Problem
Existing medicament delivery devices face challenges in securely assembling and maintaining a drive mechanism to transmit force effectively, particularly in large volume delivery devices, requiring additional components and clean room environments for aseptic assembly.
Innovation Solution
A drive mechanism system comprising a drive housing with ridges, protrusions, and a drive release latch, secured by a drive holder, allows for aseptic assembly and operation without the need for a clean room, using a telescopic mechanism with a piston and spring for force transmission.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If additional components are added to secure the drive mechanism in place, then the drive can appropriately transmit force with complicated device configurations, but the device complexity increases and assembly becomes more difficult
Solution Approach 1:
The drive housing integrates multiple functions into a single component structure, combining the drive mechanism with securing features (ridges, protrusions) and force transmission elements (piston, detent) into one unified assembly that fits into the drive holder, reducing the need for separate additional components
Solution Approach 2:
The drive mechanism is designed as a nested structure where the piston mechanism is housed within the drive housing, which in turn fits into the drive holder, creating a compact integrated assembly that maintains reliability while minimizing overall complexity
2Reliability
If additional components are added to secure the drive mechanism, then force transmission is improved, but the manufacturing cost and assembly environment requirements increase
Solution Approach 1:
The drive mechanism is segmented into distinct functional modules (drive housing with securing features, piston mechanism, detent system) that can be manufactured separately and then assembled together, allowing for easier manufacturing and assembly without requiring clean room environments
Solution Approach 2:
The drive mechanism incorporates self-securing features where the ridges and protrusions automatically engage with the drive holder upon assembly, and the detent mechanism provides automatic locking, eliminating the need for additional fastening components or complex assembly procedures
3Force
If the drive mechanism creates significant force to push medicament through the fluid path, then delivery effectiveness is improved, but the force must be counteracted and transmitted through additional components
Solution Approach 1:
The drive housing serves multiple functions simultaneously: it contains the piston mechanism, provides structural support for force transmission, incorporates securing features (ridges and protrusions) for attachment, and guides the force transmission path, eliminating the need for separate components for each function
Solution Approach 2:
The drive housing acts as an intermediary structure that receives the significant force from the piston mechanism and distributes it through integrated force transmission paths to the medicament container, while simultaneously providing securing features to maintain structural integrity during force transmission
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables aseptic and cost-effective assembly of large volume delivery devices, maintaining sterility and ensuring efficient medicament delivery with flexible manufacturing conditions, suitable for biological medicaments of varying viscosities.
Implementation Method 1
The piston mechanism can include a piston, a drive outer sleeve, and a detent. The pair of walls can be configured to interact with the drive release latch.
Data Source
AI summary
A system for delivering a medicament is provided. The system can include a drive mechanism configured to drive a plunger of a medicament container. The medicament container may be contained in a container sled, and the drive mechanism can be securely held by a drive holder adjacent the container sled. The drive holder can be secured within an external housing of the system allowing the container to move with the container sled to form a connection with a fluid delivery pathway.