Inlet Conduit Pouch for Biologic Sample Viability
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Solution Overview
Problem
Current methods for preserving and dispensing biologic materials, such as cells, face challenges in maintaining viability during cryopreservation, particularly in the intermediate temperature zone, and require separate counter samples for testing, which can lead to contamination and loss.
Innovation Solution
A device with a hollow body and inlet conduit that allows for the generation of a pilot sample pouch within the same storage chamber, ensuring the counter sample is subjected to the same conditions as the main sample, minimizing contamination and loss by integrating storage and dispensing functions.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If separate counter samples are stored in different locations, then the main sample can be stored in optimal conditions, but the counter sample may be contaminated or lost and requires separate manipulation
Solution Approach 1:
The patent merges the storage of the main liquid sample and the counter sample into a single integrated device. The inlet conduit is configured to receive both the main sample in the chamber and the counter sample in a pouch, eliminating the need for separate storage locations and reducing the risk of contamination or loss associated with handling separate samples.
Solution Approach 2:
The counter sample pouch is nested within the inlet conduit of the hollow body, which itself contains the main liquid sample chamber. This nested arrangement allows both samples to be stored together in a compact configuration, ensuring the counter sample remains protected and associated with the main sample throughout storage and dispensing operations.
2Adaptability or versatility
If the inlet conduit is made closable in multiple axial positions, then counter samples can be generated within the same device, but the device complexity increases
Solution Approach 1:
The inlet conduit is designed with dynamic closing capabilities at multiple axial positions, allowing it to transition between open and closed states at different locations. This dynamic behavior enables the formation of sealed pouches containing counter samples while maintaining relative simplicity in the overall device structure through controlled sealing actions rather than complex mechanical assemblies.
3Volume of stationary object
If counter samples are delocalized in the storage medium, then storage space is optimized, but it becomes difficult to use the correct counter sample for control and testing
Solution Approach 1:
The inlet conduit acts as an intermediary structure that organizes and positions the counter sample pouch within the device. This intermediary arrangement ensures the counter sample remains localized and easily accessible for control and testing operations, while still utilizing the storage space efficiently within the hollow body structure.
Data Source
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AI summary
Device for storing and dispensing a liquid sample comprising a hollow body (8) comprising a chamber for storing the liquid sample and dispensing means for extracting the liquid sample from the chamber, wherein the device further comprises an inlet conduit (5) configured for introducing the liquid sample to the chamber, the inlet conduit (5) being configured to be closable in at least two axial positions (52, 51) in order to generate at least one pouch (53) in said inlet conduit for storing a pilot liquid sample. Method for storing and dispensing a liquid sample.