Inspection Kit Liquid-Absorbing Part Capillary Overflow Control
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Solution Overview
Problem
Existing immunochromatography inspection kits face issues with incorrect results due to excessive sample dripping, leading to false negatives and false positives, as the surplus sample overflows and fails to flow correctly through the reagent device, inhibiting antigen-antibody reactions and color development.
Innovation Solution
The inspection kit incorporates a liquid-absorbing part near the sample-dripping area, guiding any excess sample via capillary action in a direction different from the primary flow, ensuring only the appropriate amount of sample reaches the reagent device for accurate results, regardless of whether sensitization liquid is used.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If the sample-dripping part allows free flow of sample liquid, then the operation is simple and quick, but excessive sample causes overflow and incorrect inspection results
Solution Approach 1:
The patent introduces a liquid-absorbing part as an intermediary component between the sample-dripping part and the reagent device. This mediator absorbs excess sample liquid through capillary action and guides it to a predetermined discharge position, preventing overflow while maintaining simple operation. The liquid-absorbing part acts as a buffer that reconciles the contradiction between ease of operation and reliability of inspection results.
2Device complexity
If no liquid-absorbing part is provided, then the device structure is simple, but surplus sample overflows and inhibits antigen-antibody reactions
Solution Approach 1:
The liquid-absorbing part is constructed from porous material that utilizes capillary action to absorb and guide excess sample liquid. The porous structure enables the material to selectively absorb liquid based on surface tension and capillary forces, directing the excess sample to the discharge position without requiring complex mechanical structures. This resolves the contradiction by adding minimal structural complexity while significantly improving reaction accuracy.
3Object-affected harmful factors
If the case is enclosed to improve operability and reduce infection risks, then safety is improved, but excess sample has no controlled discharge path
Solution Approach 1:
The patent extracts the excess sample liquid from the main reaction flow and directs it to a predetermined discharge position within the enclosed case. The liquid-absorbing part separates the excess sample from the reaction area and channels it to a safe discharge location, preventing uncontrolled overflow while maintaining the enclosed protective structure. This resolves the contradiction by providing controlled discharge paths within the enclosed case, maintaining both safety and operational ease.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This design ensures precise and correct inspection results by preventing surplus sample overflow, allowing for proper antigen-antibody interaction and color development, thereby reducing false negatives and positives, and maintaining sensitivity even with excessive sample dripping.
Implementation Method 1
a liquid-absorbing part guiding, according to capillary action, a remainder of the sample in a second direction differing from the first direction
Implementation Method 2
the colored particle-labeled antibody is eluted and removed according to capillary action there-through
Data Source
AI summary
Provided is an inspection kit that proper inspection can be performed even if a tester drips a remainder of sample. The inspection kit includes: a reagent device having a sample-dripping part, the reagent device being capable of making a sample dripped on the sample-dripping part flow in a first direction from an upstream side toward a downstream side; and a case surrounding the reagent device. A liquid-absorbing part is provided with a portion near the sample-dripping part of the case, the liquid-absorbing part guiding, according to capillary action, the remainder of the sample in a second direction differing from the first direction.