Closed Loop Insulin Control with Accuracy Indication

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Solution Overview

Problem

Closed loop control systems for insulin delivery in diabetic management face safety and accuracy issues due to potential failures in glucose sensors and infusion components, leading to unreliable insulin administration.

Innovation Solution

A method and device for monitoring physiological conditions and automatically administering medication, which includes continuous monitoring, detecting impending medication thresholds, retrieving signals, determining accuracy indications, and executing medication administration based on these indications to ensure safe and accurate insulin delivery.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If closed loop control systems are implemented for automated insulin delivery, then insulin delivery accuracy is improved, but system reliability deteriorates due to potential sensor and infusion component failures

Engineering Contradiction:
Improveinsulin delivery accuracyVSAvoidsystem reliability
Core Design Contradiction:
Measurement precisionVSReliability

Solution Approach 1:

The system performs preliminary actions by continuously monitoring glucose levels and predicting future glucose trends before actual hypoglycemic or hyperglycemic events occur. The control algorithm anticipates medication needs and adjusts insulin delivery proactively, preventing extreme glucose levels rather than merely reacting to them.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system implements continuous feedback loops where glucose sensor data is constantly fed back to the control algorithm, which then adjusts insulin delivery rates in real-time. This closed-loop feedback mechanism ensures that insulin delivery accuracy is maintained while the system can detect and respond to sensor failures or anomalies through abnormal feedback patterns.

Inventive Principle:
Principle #23Feedback

2Measurement precision

If continuous glucose monitoring is performed to enable real-time insulin adjustment, then insulin delivery accuracy is improved, but device complexity increases due to multiple monitoring and control components

Engineering Contradiction:
Improveglucose level monitoring accuracyVSAvoidsystem complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The system achieves multi-functionality by integrating glucose sensing, data processing, control algorithm execution, and insulin delivery control into a unified platform. The single device performs multiple functions including continuous glucose monitoring, predictive analytics, automated insulin dosing calculations, and direct communication with the insulin pump, thereby reducing the need for separate standalone devices.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The patent combines the glucose monitor, control unit with processing capabilities, and insulin pump interface into an integrated system. By merging these previously separate components into a cohesive unit, the system reduces overall device complexity while maintaining continuous monitoring and automated control functions.

Inventive Principle:
Principle #5Merging (Combining)

Data Source

PatentUS10406286B2Closed loop control with reference measurement and methods thereof
Publication Date: 2019.09.10 ABBOTT DIABETES CARE INC
  • US10406286B2 patent drawing
  • US10406286B2 patent drawing
  • US10406286B2 patent drawing

AI summary

Methods, system and devices for monitoring a plurality of parameters associated with a closed loop control operation including continuously monitoring a physiological condition and automatic administration of a medication, detecting an impending administration of the medication level exceeding a predetermined threshold level, retrieving one or more signals associated with the monitored physiological condition, determining an accuracy indication of the retrieved one or more signals associated with the monitored physiological condition, and executing the administration of the medication level based on the accuracy indication are provided.