Insulin Pump Concentration Sensing for Accurate Multi-Strength Dosing
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Insulin delivery devices that accommodate various insulin concentrations face the risk of user error in setting adjustments, leading to potential over-dosing or under-dosing, which can cause serious health issues like hypoglycemia or hyperglycemia.
Innovation Solution
A sample analyzer with a sample receiving region and analytical reagent that reacts with a fluid sample to modify its color, allowing a detector to determine the insulin concentration, and signal processing components to provide an indication for proper device setting adjustments.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Adaptability or versatility
If insulin delivery devices accommodate various insulin concentrations (U100, U200, U500, U1000), then the device versatility is improved, but the risk of user error in setting adjustments increases
Solution Approach 1:
The system performs preliminary detection of insulin concentration in the reservoir before and during delivery. The optical sensor detects the concentration of insulin in the fluid within the reservoir, and the controller adjusts delivery parameters based on this detected concentration, preventing user error in setting adjustments
Solution Approach 2:
The system implements continuous feedback by detecting insulin concentration in real-time and automatically adjusting delivery parameters. The controller receives feedback from the optical sensor about the actual insulin concentration and modifies pump settings accordingly, creating a closed-loop control system that eliminates the need for manual concentration setting
2Device complexity
If manual adjustment of pump settings for insulin concentration is required, then the device complexity is reduced, but the risk of over-dosing or under-dosing increases
Solution Approach 1:
The system performs self-service by automatically detecting insulin concentration and adjusting delivery parameters without user intervention. The optical sensor and controller work autonomously to determine the correct dosing parameters based on the detected insulin concentration, eliminating manual adjustment steps and associated health risks
Solution Approach 2:
The system replaces manual mechanical adjustment of pump settings with an automated optical detection and control system. The optical sensor detects insulin concentration optically, and the controller automatically translates this information into appropriate pump delivery parameters, substituting manual mechanical adjustment with automated sensing and control
3Measurement precision
If optical sensors and automated control systems are integrated into insulin pumps, then dosing accuracy is improved, but the device complexity increases
Solution Approach 1:
The system achieves multi-functionality by using the optical sensor and controller for multiple purposes: detecting insulin concentration, determining delivery parameters, and providing real-time monitoring. This universal approach consolidates multiple functions into integrated components, managing device complexity through functional consolidation rather than adding separate dedicated systems
Solution Approach 2:
The system merges the optical detection system, concentration analysis algorithms, and pump control functions into an integrated unit. The controller combines information from the optical sensor with delivery parameters to automatically determine optimal dosing, merging sensing, processing, and actuation functions to manage complexity through integration
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Ensures accurate insulin concentration determination, reducing the risk of over- or under-dosing by enabling non-invasive, miniaturized, and portable insulin delivery devices with improved safety and efficacy.
Implementation Method 1
The analytical reagent is configured to react with the fluid sample to modify a color of the fluid sample
Implementation Method 2
a sensor assembly with a detector configured to determine the color of the reacted fluid sample
Data Source
AI summary
Systems and methods for determining medicament concentrations within medicament delivery devices are disclosed. A medicament delivery device can include a fluid path comprising a reservoir in fluid communication with an outlet port, in which the device is actuatable to drive fluid through the fluid path, from the reservoir and out of the outlet port. A sample receiving chamber of the delivery device is configured to receive a fluid sample from the fluid path. The sample receiving chamber includes an analytical reagent configured to react with the fluid sample to modify the color of the fluid sample. A sensor assembly of the delivery device includes a detector configured to determine the color of the reacted fluid sample and one or more signal processing components configured to provide an indication of the analyte concentration in the fluid sample based at least in part on the color determination.