Integrated Dialyzer with Magnetic Pump Rotor

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Conventional blood treatment systems for renal dysfunction, such as hemodialysis and hemofiltration, are complex and require extensive setup, leading to increased setup time, potential for human error, and higher costs due to the need for multiple components and lengthy extracorporeal tubing.

Innovation Solution

A dialyzer system integrated with a magnetically driven and levitating pump rotor, along with pressure sensor chambers, and a treatment module that generates dynamic magnetic fields to simplify setup and enhance blood treatment performance by consolidating multiple technologies into a single, compact unit.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Loss of time

If conventional blood treatment systems use multiple separate components and lengthy extracorporeal tubing, then blood treatment function is provided, but setup time increases and device complexity increases

Engineering Contradiction:
Improvesetup timeVSAvoidsystem complexity
Core Design Contradiction:
Loss of timeVSDevice complexity

Solution Approach 1:

The patent integrates the pump, pressure sensors, and dialyzer into a single consolidated unit. The pump is positioned within the dialyzer housing, and pressure sensors are embedded in the housing structure, eliminating the need for separate external components and lengthy tubing connections, thereby reducing setup time and system complexity

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The dialyzer housing serves multiple functions: it contains the pump mechanism, houses pressure sensors for monitoring, provides fluid pathways, and supports the semi-permeable membrane. This multi-functional integration reduces the number of separate components needed in the blood treatment system

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Ease of operation

If conventional systems use multiple separate components, then blood treatment is achieved, but the number of components and setup steps increase

Engineering Contradiction:
Improvesetup simplicityVSAvoidnumber of components
Core Design Contradiction:
Ease of operationVSDevice complexity

Solution Approach 1:

The pump, pressure sensors, and dialyzer are merged into a single integrated assembly. The pump is positioned within the dialyzer housing with direct fluid communication, and pressure sensors are embedded in the housing, eliminating multiple separate components and simplifying the setup process

Inventive Principle:
Principle #5Merging (Combining)

3Object-affected harmful factors

If conventional systems use lengthy extracorporeal tubing, then blood treatment function is provided, but treatment costs increase and hemolysis risk increases

Engineering Contradiction:
Improvehemolysis riskVSAvoidtubing length
Core Design Contradiction:
Object-affected harmful factorsVSLength of stationary object

Solution Approach 1:

The pump and dialyzer are integrated into a single unit with direct fluid communication, eliminating the need for lengthy extracorporeal tubing. This reduces the surface area in contact with blood, thereby lowering hemolysis risk and treatment costs

Inventive Principle:
Principle #5Merging (Combining)

4Ease of repair

If conventional systems use multiple separate components, then blood treatment is achieved, but maintenance requirements increase

Engineering Contradiction:
Improvemaintenance requirementsVSAvoidnumber of components
Core Design Contradiction:
Ease of repairVSDevice complexity

Solution Approach 1:

The pump, pressure sensors, and dialyzer are integrated into a single maintenanceable unit. This consolidation reduces the number of separate components that require individual maintenance, simplifying repair procedures and reducing overall maintenance requirements

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The solution reduces setup time, minimizes the length of extracorporeal tubing, lowers hemolysis risk, and decreases maintenance requirements, resulting in reduced treatment costs and improved patient care efficiency.

Implementation Method 1

a pump impeller within the housing that is magnetically-drivable to force fluid through lumens of the hollow fibers

Methodology Applied
Scientific EffectMagnetic drive: Magnetic Field

Implementation Method 2

The transportation of the small molecular substances through the semi-permeable membrane is determined mainly by the differences in concentration between the dialysate and the blood

Methodology Applied
Scientific EffectPressure differential: Pressure Gradient

Implementation Method 3

Diffuse mass transport is predominant in hemodialysis (HD)

Methodology Applied
Scientific EffectDiffusion: Diffusion

Implementation Method 4

in hemofiltration (HF) convective mass transport through a membrane is used

Methodology Applied
Scientific EffectConvection: Convection

Implementation Method 5

pressure sensor chambers with flexible membranous walls against which corresponding pressure transducers of the treatment modules can interface to detect arterial and/or venous pressures

Methodology Applied
Scientific EffectPressure detection:

Data Source

PatentUS11730871B2Blood treatment systems
Publication Date: 2023.08.22 FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH
  • US11730871B2 patent drawing
  • US11730871B2 patent drawing
  • US11730871B2 patent drawing

AI summary

Dialyzer systems can consolidate multiple technologies and functionalities of blood treatment systems in a significantly integrated fashion. For example, this disclosure describes dialyzer systems that include a magnetically driven and magnetically levitating pump rotor integrated into the dialyzer. Such a dialyzer can be used with treatment modules that include a magnetic field-generating pump drive unit. In some embodiments, the dialyzers include pressure sensor chambers with flexible membranes with which corresponding pressure transducers of the treatment modules can interface to detect arterial and/or venous pressures.