Integrated Filtration Assembly for Low-Contamination Microbiological Testing

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Solution Overview

Problem

Conventional filtration assemblies for microbiological testing require manual handling steps that can lead to contamination and inconsistent test results due to unprotected filter elements and multiple handling steps, resulting in handling errors and variability between tests.

Innovation Solution

A filtration assembly with a self-supporting membrane support and integrated reservoir and lid device, allowing for snap-fit connections and a drain member, which enables seamless filtration and incubation without manual handling of the filter element, ensuring reproducibility and protection from contamination.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If manual handling steps are used to transfer the filter element, then the filter element can be accessed for incubation, but contamination risk increases and handling errors occur

Engineering Contradiction:
Improveaccess to filter elementVSAvoidcontamination risk
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The filter element is merged with the reservoir to form an integrated unit. The reservoir serves dual purposes: collecting filtered fluid during filtration and serving as the incubation container afterward. This eliminates the need to separate and manually handle the filter element, thereby reducing contamination risk while maintaining operational ease.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The reservoir is designed to perform multiple functions: it acts as the fluid collection container during filtration and then becomes the incubation vessel for the filter element. This multi-functionality eliminates the need for separate handling steps and reduces contamination opportunities.

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Ease of operation

If multiple handling steps are used to transfer the filter element, then the filter element can be moved to incubation, but test consistency deteriorates

Engineering Contradiction:
Improvetransfer capabilityVSAvoidtest consistency
Core Design Contradiction:
Ease of operationVSManufacturing precision

Solution Approach 1:

By combining the filter element support structure with the reservoir, the system creates a single integrated unit that moves together through all steps. This eliminates variability introduced by multiple manual transfer operations, ensuring consistent test conditions and reproducible results.

Inventive Principle:
Principle #5Merging (Combining)

3Adaptability or versatility

If the filter element is exposed during handling, then it can be transferred to incubation, but protection from contamination is reduced

Engineering Contradiction:
Improvetransfer flexibilityVSAvoidcontamination exposure
Core Design Contradiction:
Adaptability or versatilityVSObject-affected harmful factors

Solution Approach 1:

The filter element remains integrated with the reservoir throughout the entire process, eliminating exposure to the external environment during transfer operations. The reservoir acts as a protective enclosure that maintains sterility while allowing the filter element to be accessed for incubation.

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The assembly reduces contamination risks and ensures consistent test conditions by protecting the filter membrane during handling and incubation, improving reproducibility and reducing the risk of errors in microbiological testing.

Implementation Method 1

a filtration membrane (11) capable of capturing microorganisms of interest

Methodology Applied
Scientific EffectFiltration: Filter (physical)

Implementation Method 2

a drain member (30) removably and fluid tightly attachable to the membrane support (10) to define a drain channel space (13) adjacent to the filtration membrane (11)

Methodology Applied
Scientific EffectGravity drainage: Gravitation

Data Source

PatentEP3678760B1Filtration assembly and method for microbiological testing
Publication Date: 2025.10.29 MERCK PATENT GMBH
  • EP3678760B1 patent drawingFigure 1
  • EP3678760B1 patent drawingFigure 2
  • EP3678760B1 patent drawingFigure 3A~3C

AI summary

The invention concerns a filtration assembly for microbiological testing and a method of using the filtration assembly for that purpose. The filtration assembly (1) comprises a ring-like membrane support (10) holding a filtration membrane (11), a cylindrical reservoir (20) of which opposite axial ends have openings and one axial opening is removably and fluid-tightly attachable to the membrane support (10) to define a sample volume adjacent to the filtration membrane (11) on one axial side of the membrane support (10); and a lid device (40) removably and fluid tightly attachable to the other axial opening of the reservoir (20) to close the opening. Further, the lid device (40) is removably and fluid tightly attachable to the membrane support (10) so as to seal the one axial side of the membrane support (10) from the environment.