Integrated Flow Diverter and Coil for Aneurysm Occlusion
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Solution Overview
Problem
Current medical devices for treating aneurysms, such as balloon-type aneurysms, face challenges including high recanalization rates, prolonged procedure times, increased radiation exposure, and inability to effectively treat aneurysms at bifurcations, as well as complications like stenosis and the need for long-term blood thinner use.
Innovation Solution
An occlusive device comprising a marker band and a ribbon-like strand of porous mesh formed from braided wires, which is configured to expand and position over the aneurysm neck, promoting endothelialization and reducing blood flow into the aneurysm, while being deliverable through a catheter and deployable within the aneurysm sac.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If platinum coils are delivered to the aneurysm sac, then the aneurysm can be treated, but the recanalization rate is about 30% and procedure time is prolonged
Solution Approach 1:
The patent combines the flow diverter function and coil delivery function into a single integrated device. The flow diverter portion is positioned at the aneurysm neck to prevent blood flow into the aneurysm, while the coil portion is delivered into the aneurysm sac to promote thrombosis. This unified structure eliminates the need for separate delivery procedures, reducing procedure time while maintaining treatment effectiveness and lowering recanalization rates.
2Reliability
If stent and coil are used together, then aneurysm can be treated, but the procedure becomes more complex and requires longer procedure time
Solution Approach 1:
The device merges the stent/flow diverter component and the coil component into a single integrated structure that is delivered as one unit. The flow diverter portion performs the stent function of preventing blood flow into the aneurysm, while the coil portion performs the embolization function. This integration simplifies the procedure by eliminating the need to separately deploy stents and coils, reducing procedural complexity while maintaining the therapeutic benefits of combined therapy.
3Reliability
If flow diverter is positioned over the aneurysm neck, then blood flow into aneurysm is prevented, but stenosis may occur and blood thinners are required indefinitely
Solution Approach 1:
The integrated device combines the flow diverter portion that prevents blood flow into the aneurysm with the coil portion that promotes thrombosis within the aneurysm sac. The coil structure provides a scaffold for thrombus formation and eventual organization, which can reduce the long-term need for anticoagulation therapy compared to flow diverters alone. This dual mechanism addresses the harmful effects by providing both flow diversion and thrombosis promotion in a single device.
4Reliability
If multiple flow diverters are required per aneurysm, then blood flow diversion is ensured, but procedure complexity and time increase
Solution Approach 1:
The integrated device delivers both the flow diverter function and the coil embolization function in a single procedural step. The flow diverter portion is positioned at the aneurysm neck while the coil portion is simultaneously delivered into the aneurysm sac, eliminating the need to deploy multiple separate flow diverters or to perform sequential procedures. This significantly improves procedure efficiency while ensuring adequate blood flow diversion and aneurysm occlusion.
Data Source
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AI summary
Devices and methods for treating vascular defects, such as, for example, balloon-type aneurysms, are described herein. In one embodiment, an apparatus includes an insertion portion and an expandable implant. The expandable implant is configured to be deployed in an aneurysm and is coupled to the insertion portion. The expandable implant has a first portion and a second portion coupled to the first portion. The expandable implant is movable between a first configuration in which the first portion and the second portion are substantially linearly aligned and a second configuration in which the second portion at least partially overlaps the first portion.