Integrated Hemostat Delivery Device for Co-Administration

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Solution Overview

Problem

Current methods for delivering hemostatic agents in surgical procedures require separate devices for powders and liquids, which are cumbersome, time-consuming, and often result in premature curing or washing away of the medicants due to the need for two-handed operation and multiple trocar insertions, leading to inefficient hemostasis and sealing.

Innovation Solution

A single-hand operated device that co-delivers a liquid medicant and a powder medicant through integrated expression subunits, allowing synchronous or sequential delivery without pre-mixing, using a dual barrel syringe and a resiliently compressible bellows-based powder delivery system, ensuring precise application and minimizing the risk of premature curing or washing away.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of manufacture

If separate devices are used for delivering powder and liquid hemostatic agents, then each device can be optimized for its specific medicant type, but the overall procedure becomes cumbersome, time-consuming, and requires two-handed operation with multiple trocar insertions

Engineering Contradiction:
Improvedevice optimizationVSAvoidmultiple devices
Core Design Contradiction:
Ease of manufactureVSDevice complexity

Solution Approach 1:

The patent combines separate powder delivery device and liquid delivery device into a single integrated device. The powder reservoir and liquid reservoir are integrated into one housing, with coordinated delivery mechanisms that allow simultaneous or sequential delivery through a single trocar. This eliminates the need for multiple devices while maintaining optimization for both medicant types.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The integrated device performs multiple functions: it can deliver powder hemostatic agents, liquid hemostatic agents, and potentially both simultaneously or sequentially. The device is designed to handle different medicant types through a single unified platform, reducing procedural complexity while maintaining versatility.

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Adaptability or versatility

If separate devices are used for powder and liquid delivery, then each medicant can be delivered independently, but the procedure requires two-handed operation and multiple trocar insertions leading to time loss and premature curing

Engineering Contradiction:
Improveindependent deliveryVSAvoidprocedural time
Core Design Contradiction:
Adaptability or versatilityVSLoss of time

Solution Approach 1:

The integrated device enables continuous delivery action by coordinating powder and liquid delivery mechanisms to operate simultaneously or in rapid succession through a single trocar. This eliminates the time loss associated with withdrawing and reinserting devices, and prevents premature curing by maintaining continuous delivery flow.

Inventive Principle:
Principle #20Continuity of useful action

Solution Approach 2:

The device structure allows one delivery mechanism to be nested within or alongside the other, with the powder delivery system and liquid delivery system integrated in a compact arrangement. This enables coordinated operation through a single access point while maintaining independent control of each medicant delivery.

Inventive Principle:
Principle #7Nested doll (Nesting)

3Ease of operation

If separate devices are used, then powder and liquid can be delivered sequentially, but the risk of washing away powder or premature curing of liquid increases

Engineering Contradiction:
Improvesequential deliveryVSAvoidhemostasis effectiveness
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The integrated device enables periodic or pulsed delivery of powder and liquid medicants in a coordinated sequence. The delivery mechanisms can be activated in controlled intervals, allowing powder to be deposited first followed immediately by liquid, or alternating pulses, thereby preventing washing away while maintaining reliability of hemostasis.

Inventive Principle:
Principle #19Periodic action

Solution Approach 2:

The device allows preliminary delivery of powder hemostatic agent to the target site before delivering the liquid medicant. This preliminary action establishes a foundation that prevents the liquid from washing away, while the integrated design ensures immediate subsequent delivery to maintain effectiveness.

Inventive Principle:
Principle #10Preliminary action

4Productivity

If a single integrated device is used for co-delivery, then procedural time is reduced and delivery precision is improved, but the device structure becomes more complex

Engineering Contradiction:
Improvedelivery efficiencyVSAvoidintegrated structure
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The integrated device is segmented into distinct functional modules: a powder reservoir section, a liquid reservoir section, and coordinated delivery mechanisms for each. This segmentation allows independent optimization of each medicant delivery system while integrating them into a single unified device that improves productivity through simultaneous or sequential delivery capability.

Inventive Principle:
Principle #1Segmentation

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables efficient, precise, and rapid delivery of hemostatic agents, enhancing tissue interface bonding and sealing, as demonstrated by improved peel strength and ease of peeling in testing scenarios, while reducing procedural time and complexity.

Implementation Method 1

The powder delivery pump comprises a resiliently compressible bellows and a compartment filled with the powder medicant

Methodology Applied
Scientific EffectCompression: Compression

Implementation Method 2

co-delivery of a liquid medicant and a powder medicant onto a tissue or wound

Methodology Applied
Scientific EffectMixing:

Data Source

PatentEP3190980B1Devices for co-delivery of liquid and powdered hemostats and sealants
Publication Date: 2020.01.29 ETHICON INC
  • EP3190980B1 patent drawingFigure 1~2b
  • EP3190980B1 patent drawingFigure 3a~5
  • EP3190980B1 patent drawingFigure 6A~6B

AI summary

The present invention is directed to an integrated delivery device that is operable with one hand and provides co-delivery of a liquid medicant and a powder medicant onto a tissue or wound from a liquid medicant expression subunit and a powder medicant expression subunit. Each expression subunit having an actuator for the liquid medicant and the powder medicant contained therein that are positioned in close proximity to one other at a proximate end of said expression subunits and delivery cannulas for each of said expression subunits that positioned in close proximity to one other at a distal end of said expression subunits. The present invention also relates to method for using such integrated devices.