Integrated Medical Imaging and In-Vitro Diagnostic System

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Solution Overview

Problem

Radiology departments without easy access to central labs face challenges in assessing kidney function for patients undergoing CT scans, leading to potential acute kidney injury and increased patient mortality due to delayed or cancelled appointments, as they rely on external eGFR measurements.

Innovation Solution

Integration of a portable medical imaging system with an in-vitro-diagnostic device and control unit that allows for rapid measurement of creatinine levels and eGFR calculation at the point of care, enabling simultaneous medical imaging and diagnostic testing, including contrast-enhanced imaging, using a portable tablet-based system with docking structures for sample handling and sensing.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If radiology departments rely on central labs for eGFR measurements, then diagnostic accuracy is maintained, but patient waiting time increases and appointment cancellation risk increases

Engineering Contradiction:
ImproveeGFR measurement accuracyVSAvoidpatient waiting time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent combines the medical imaging device with an in-vitro-diagnostic device into an integrated system. The control device operates both the imaging modality and the diagnostic device, allowing simultaneous or coordinated execution of imaging and eGFR measurement functions. This merging eliminates the need for separate central lab processing, enabling immediate eGFR results at the point of care while maintaining diagnostic accuracy through the same control infrastructure.

Inventive Principle:
Principle #5Merging (Combining)

2Object-affected harmful factors

If CT scan appointments are cancelled to process creatinine tests externally, then patient safety is improved, but diagnostic delay increases and patient mortality risk increases

Engineering Contradiction:
Improveacute kidney injury riskVSAvoiddiagnostic delay
Core Design Contradiction:
Object-affected harmful factorsVSLoss of time

Solution Approach 1:

The system performs eGFR measurement as a preliminary action before the CT scan procedure. By integrating the diagnostic device with the imaging system, creatinine testing is completed in advance during the same visit, eliminating the need to cancel or delay the scheduled CT scan. This preliminary assessment of kidney function allows safe contrast administration while maintaining the original appointment schedule, thereby preventing both acute kidney injury and diagnostic delays.

Inventive Principle:
Principle #10Preliminary action

3Loss of time

If standalone point-of-care devices are used for rapid creatinine measurement, then patient waiting time is reduced, but device complexity and integration requirements increase

Engineering Contradiction:
Improvetest processing timeVSAvoidsystem integration complexity
Core Design Contradiction:
Loss of timeVSDevice complexity

Solution Approach 1:

The control device serves multiple functions by operating both the medical imaging device and the in-vitro-diagnostic device. This multi-functional capability allows a single control system to manage diverse operations including image acquisition, contrast agent administration, and eGFR measurement. The universal control interface reduces integration complexity compared to completely separate systems, as the same control hardware and software infrastructure handles both imaging and diagnostic functions.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Data Source

PatentEP4032477B1Medical imaging system with integrated in-vitro-diagnostic device
Publication Date: 2024.10.02 SIEMENS HEALTHINEERS AG
  • EP4032477B1 patent drawingFigure 1~2
  • EP4032477B1 patent drawingFigure 3~4
  • EP4032477B1 patent drawingFigure 5~6

AI summary

The invention relates in one aspect to a medical imaging system, comprising - a medical imaging device for medical imaging of a patient, - an in-vitro-diagnostic device for in-vitro-diagnostic testing of a sample, - a control device, wherein the control device is configured to operate the medical imaging device, wherein the control device is further configured to operate the in-vitro-diagnostic device.