Integrated Instruction File Control for Detection Composition Preparation

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Solution Overview

Problem

The inefficiency of producing and managing multiple work processing files for each preparation work in automatic detection-composition preparation instruments, leading to increased complexity and difficulty in editing, modifying, or maintaining these files, especially when common work actions are involved and developers change.

Innovation Solution

A method and device that utilize a single integrated instruction file and work data file, allowing for the generation of a work data file based on user selection, which includes time-series work actions for nucleic acid extract and reaction solution preparation, and uses instruction name information and processing information to implement work actions in the preparation instrument, enabling efficient control and management of various preparation works.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If multiple work processing files are produced for each preparation work, then the preparation instrument can perform various preparation works, but the complexity of managing and maintaining these files increases

Engineering Contradiction:
Improvepreparation work varietyVSAvoidfile management complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent segments the work processing system into two distinct components: a master work processing file that contains common instructions for all preparation works, and multiple sub-work processing files that contain specific instructions for each type of preparation work. This segmentation allows the system to maintain versatility across different preparation works while simplifying management by centralizing common operations in the master file.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent merges common work actions and instructions from multiple preparation works into a single master work processing file. By combining shared operations (such as nucleic acid extraction steps, reaction solution preparation steps, and common instrument control instructions) into the master file, the system reduces redundancy and simplifies maintenance while still supporting diverse preparation workflows through the sub-files.

Inventive Principle:
Principle #5Merging (Combining)

2Adaptability or versatility

If multiple work processing files are produced for each preparation work, then specific preparation protocols can be defined, but the difficulty of editing and modifying these files increases

Engineering Contradiction:
Improvepreparation protocol specificityVSAvoidfile editing ease
Core Design Contradiction:
Adaptability or versatilityVSEase of manufacture

Solution Approach 1:

By segmenting the file structure into a master file and sub-files, the patent enables targeted editing. Users can modify specific preparation protocols by editing only the relevant sub-work processing file without affecting other protocols, while common modifications can be made once in the master file and automatically applied across all sub-files, significantly reducing editing difficulty.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The master work processing file serves as a universal template that can be applied to multiple different preparation works. By defining common operations and parameters in the master file that can be selectively invoked by different sub-files, the system maintains protocol specificity while enabling efficient editing through centralized management of common elements.

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Productivity

If multiple work processing files are produced for each preparation work, then complete preparation workflows can be specified, but the time required to maintain and update these files increases

Engineering Contradiction:
Improvepreparation workflow completenessVSAvoidfile maintenance time
Core Design Contradiction:
ProductivityVSLoss of time

Solution Approach 1:

By merging common workflows and instructions into the master work processing file, the patent eliminates redundant maintenance efforts. When a common operation needs updating (such as a standard nucleic acid extraction step or reaction solution preparation procedure), the change is made once in the master file and automatically reflected in all sub-files that utilize that common operation, dramatically reducing maintenance time while maintaining complete workflow specifications.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent performs preliminary organization of work actions by categorizing them as either common (placed in the master file) or specific (placed in sub-files) during the initial setup phase. This preliminary classification enables efficient future maintenance by establishing a structured hierarchy that automates the propagation of updates, reducing the time required for subsequent modifications.

Inventive Principle:
Principle #10Preliminary action

4Productivity

If multiple work processing files are produced for each preparation work, then all necessary instructions can be provided, but the complexity of file interoperation increases

Engineering Contradiction:
Improveinstruction completenessVSAvoidfile interoperation complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent segments instructions into hierarchical levels: master-level instructions in the master work processing file and sub-level instructions in sub-work processing files. This segmentation creates a clear hierarchy where the master file provides the framework and sub-files provide specific implementations, simplifying interoperation by establishing well-defined parent-child relationships between files rather than requiring complex peer-to-peer coordination between multiple independent files.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The master work processing file acts as an intermediary that coordinates between different sub-work processing files. By centralizing common operations and control logic in the master file, the system simplifies interoperation - the master file serves as the primary coordinator that manages the interaction between different preparation workflow sub-files, reducing the complexity of direct inter-file communication.

Inventive Principle:
Principle #24Intermediary (Mediator)

Data Source

PatentEP3645997B1Method and device for controlling detection-composition preparation instrument
Publication Date: 2023.09.13 SEEGENE INC
  • EP3645997B1 patent drawingFigure 1~2
  • EP3645997B1 patent drawingFigure 3~4B
  • EP3645997B1 patent drawingFigure 4C~5

AI summary

Provided is a method and device for controlling a preparation instrument that prepares a detection composition used for detecting a target nucleic acid molecule in a specimen using an integrated instruction file.