Integrated Insulin Delivery with Continuous Glucose Sensor Feedback
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Solution Overview
Problem
Diabetic patients face challenges in managing their glucose levels due to the lack of continuous monitoring and the inconvenience of traditional blood glucose testing, leading to delayed detection of hyper- or hypo-glycemic conditions and increased risk of dangerous side effects.
Innovation Solution
An integrated system comprising a continuous glucose sensor, an electronics module, and an insulin delivery device that automatically adjusts insulin therapy based on internally derived data and programmable glucose boundaries, allowing for continuous glucose monitoring and insulin delivery.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If traditional self-monitoring blood glucose (SMBG) methods are used, then the device complexity is low, but the monitoring frequency is insufficient and glucose level changes are detected too late
Solution Approach 1:
The patent combines a continuous glucose sensor, an insulin delivery device, and a controller into an integrated system. The sensor continuously monitors glucose levels and transmits data to the controller, which automatically adjusts insulin delivery, eliminating the need for separate monitoring and manual decision-making processes.
Solution Approach 2:
The system enables automatic insulin delivery based on real-time glucose sensor data. The controller autonomously determines when and how much insulin to administer without requiring manual blood glucose testing or patient calculations, allowing the system to self-regulate therapy decisions.
2Reliability
If manual blood glucose monitoring is used, then the ease of operation is high, but the user must make therapy decisions which are subject to human error
Solution Approach 1:
The system implements continuous feedback loops where the glucose sensor constantly monitors blood glucose levels and transmits this information to the controller. The controller processes this real-time data and automatically adjusts insulin delivery accordingly, creating a closed-loop system that eliminates manual therapy decision-making and reduces human error.
3Measurement precision
If continuous glucose monitoring is implemented, then the monitoring precision is improved, but the device complexity and cost increase
Solution Approach 1:
The integrated system performs multiple functions through a unified platform: continuous glucose monitoring, data transmission and processing, automated therapy decision-making, and insulin delivery control. This multi-functionality reduces the need for separate devices and simplifies the overall system architecture despite the advanced capabilities provided.
Data Source
AI summary
Systems and methods for integrating a continuous glucose sensor 12, including a receiver 14, a medicament delivery device 16, a controller module, and optionally a single point glucose monitor 18 are provided. Integration may be manual, semi-automated and/or fully automated.