Integrated Optical Measurement Device for Multi-Wavelength POCT
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Solution Overview
Problem
Existing point-of-care testing (POCT) devices using lateral flow immunoassay methods are limited by the need for separate systems for visible light and fluorescence measurements, leading to large, heavy, and durable devices that are difficult to use in the field.
Innovation Solution
An integrated optical measurement device that miniaturizes and integrates multiple light sources, sensors, filters, and lenses corresponding to different wavelength bands into a single module, allowing for simultaneous measurement of colored reactions, fluorescent reactions, and time-resolved fluorescence signals.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If multiple separate systems are used for visible light and fluorescence measurements, then measurement precision is improved, but device complexity increases and portability deteriorates
Solution Approach 1:
The patent combines multiple separate optical measurement systems (visible light, fluorescence, time-resolved fluorescence) into a single integrated optical measurement device. The device includes multiple light sources (LEDs, lasers) and detectors arranged in a unified structure, allowing simultaneous or sequential execution of different measurement modes without requiring separate equipment. This merging approach maintains measurement precision while reducing device complexity and improving portability.
Solution Approach 2:
The optical measurement device is designed with multi-functionality to perform various measurement modes including visible light absorption, fluorescence, and time-resolved fluorescence measurements. The device includes configurable light sources with different wavelengths and detectors that can operate in multiple modes, making a single device universal for different measurement requirements rather than needing separate specialized systems.
2Adaptability or versatility
If multiple drive systems are integrated into a single device, then functionality is improved, but reliability deteriorates due to increased vulnerability
Solution Approach 1:
The optical measurement device is divided into independent functional modules, each handling specific measurement tasks. The device includes separate light source modules, detector modules, and control modules that can operate independently. This segmentation allows the system to maintain high functionality while improving reliability, as failures in one module do not necessarily affect other modules.
3Measurement precision
If devices are made large and heavy to accommodate multiple measurement capabilities, then measurement precision is improved, but ease of operation deteriorates due to reduced portability
Solution Approach 1:
The optical measurement device employs a compact nested structure where multiple functional components are arranged in a space-efficient manner. The device includes layered arrangements of light sources, filters, and detectors that are integrated vertically and horizontally, allowing multiple measurement capabilities to be housed in a small, portable form factor while maintaining measurement precision.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The integrated device enables compact, lightweight, and durable POCT systems capable of multi-modal optical measurements, enhancing portability and reliability while maintaining quantitative and qualitative analysis performance.
Implementation Method 1
a light source module that includes first to Nth light source units each of which irradiates light of different wavelengths to a sample
Implementation Method 2
a sensor unit that acquires image information on the sample
Implementation Method 3
a filter unit that is provided below the sensor unit, includes a plurality of filters that pass light reflected from the sample through a predetermined wavelength range
Implementation Method 4
a second light source lens that refracts or disperses the light of the second wavelength range irradiated from the second light source
Data Source
AI summary
The present invention relates to an integrated optical measurement device. The integrated optical measurement device includes a light source module that includes first to Nth light source units each of which irradiates light of different wavelengths to a sample (N is a natural number greater than or equal to 2), when a direction in which the light source module irradiates light is downward, a detection module that is provided above the light source module to detect a reaction of the sample, a sample unit that is provided below the light source module to fix the sample, and an angle mount that fixes the first to Nth light source units at a predetermined angle, in which the first to Nth light source units are fixedly installed around the detection module.