Integrated Radiation and Hyperthermia Device for Simultaneous Cancer Therapy

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Solution Overview

Problem

Conventional cancer therapies, such as radiation and thermotherapy, are not entirely satisfactory as they often require sequential administration rather than simultaneous delivery, which may not optimize the synergistic effects of radiation and heat on cancer cells.

Innovation Solution

A therapeutic device that integrates radiation therapy and thermotherapy, allowing for simultaneous spatial and temporal administration of ionizing radiation and regional hyperthermia, using a tomotherapy apparatus and a thermotherapeutic heating device, with image-guidance to ensure precise targeting and temperature control.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If radiation therapy and thermotherapy are administered sequentially in separate locations, then the treatment can be delivered using conventional separate apparatus, but the synergistic effects of radiation and heat on cancer cells are not optimized

Engineering Contradiction:
Improvetreatment effectivenessVSAvoidintegrated therapy system
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent combines radiation therapy apparatus and thermotherapy apparatus into a single integrated therapeutic device. The radiation source and heating element are merged within the same treatment chamber, allowing simultaneous delivery of both therapies to the same target area without requiring patient repositioning or separate treatment sessions.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The integrated therapeutic device performs multiple therapeutic functions simultaneously - it can deliver radiation therapy, thermotherapy, or both combined in one treatment session. The device is designed to accommodate different treatment modalities within a single apparatus, making it a universal cancer treatment platform.

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Productivity

If radiation therapy and thermotherapy are administered simultaneously in the same apparatus, then the synergistic effects are maximized, but the device complexity and control requirements increase

Engineering Contradiction:
Improvetreatment efficiencyVSAvoidintegrated control system
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The device incorporates dynamic control capabilities where the radiation source and heating element can be independently adjusted in intensity and timing. The control system allows real-time modulation of both therapy parameters during treatment, enabling adaptive delivery based on tissue response and treatment progress.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The integrated device includes monitoring systems that provide feedback on treatment delivery for both radiation and heat. This allows the control system to adjust parameters in real-time to maintain optimal treatment conditions, ensure patient safety, and maximize therapeutic effectiveness through closed-loop control.

Inventive Principle:
Principle #23Feedback

3Loss of time

If separate therapy sessions are used for radiation and thermotherapy, then each therapy can be optimized independently, but the treatment time and patient inconvenience increase

Engineering Contradiction:
Improvetotal treatment durationVSAvoidpatient mobility requirements
Core Design Contradiction:
Loss of timeVSEase of operation

Solution Approach 1:

The patent merges radiation therapy and thermotherapy into a single treatment session delivered in one location. The integrated apparatus eliminates the need for patients to travel between separate treatment facilities or undergo multiple setup procedures, consolidating both therapies into one convenient visit.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The device enables continuous simultaneous delivery of both radiation and heat therapies during the same treatment period. This eliminates idle time between separate therapy sessions and maintains continuous therapeutic action on the target tissue, maximizing treatment efficiency.

Inventive Principle:
Principle #20Continuity of useful action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach enhances the synergistic effects of radiation and heat on cancer cells, improving blood supply and oxygenation, and impairing tumor cell repair mechanisms, leading to more effective treatment outcomes.

Implementation Method 1

The radiation therapy apparatus applies an ionizing radiation to the patient

Methodology Applied
Scientific EffectIonizing radiation: Ionisation

Implementation Method 2

the thermotherapeutic heating device induces a regional hyperthermia in the patient. The term hyperthermia defines a procedure in which the body cells in the area of treatment are heated to a temperature of 40°C-46°C

Methodology Applied
Scientific EffectRegional hyperthermia: Heating

Implementation Method 3

The therapeutic device according to the invention further comprises at least one body scanner generating images of the body interior of the patient

Methodology Applied
Scientific EffectImage-guidance: Tomography

Data Source

PatentEP2288413B1Therapeutic device combining radiation therapy and thermotherapy
Publication Date: 2012.03.14 HELMHOLTZ ZENT MUENCHEN DEUT FORSCHUNGSZENTRUM FUER GESUNDHEIT & UMWELT (GMBH)
  • EP2288413B1 patent drawingFigure 1
  • EP2288413B1 patent drawingFigure 2
  • EP2288413B1 patent drawingFigure 3

AI summary

The invention relates to a therapeutic device (1) for treatment of a patient, particularly for cancer treatment, comprising a radiation therapy apparatus (2) for applying an ionizing radiation to the patient, characterized by an integrated thermotherapeutic heating device (8) for inducing a regional hyperthermia in the patient.