Interface Device for Perforable Bottles with Air Filtration

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Solution Overview

Problem

The preparation of aggressive cancer treatment liquids in oncology poses risks to nursing staff due to the introduction of air into vacuum vials containing powdered medications, leading to potential contamination and pollution during the mixing process with infusion liquids.

Innovation Solution

An interfacing device with air circulation means equipped with filtration, allowing controlled air entry and exit from the vial, retaining particles and impurities, and featuring a hollow piercing needle with a cannula and particle filters to secure the handling and preparation of the mixture.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If air is introduced into the vacuum vial to mix the powdered medication with infusion liquid, then the mixing process can be performed, but air carries pure medication particles outside the vial creating pollution and safety risks for nursing staff

Engineering Contradiction:
Improvemixing processVSAvoidmedication particle pollution
Core Design Contradiction:
Ease of operationVSObject-affected harmful factors

Solution Approach 1:

A filter is introduced as an intermediary component in the air circulation path between the vial and the external environment. The filter allows air to pass through while intercepting and retaining medication particles, thus enabling the mixing process while preventing pollution and exposure to nursing staff

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The system maintains a controlled air environment through filtration, effectively creating a protected space around the vial during the mixing process. The filtered air circulation prevents harmful medication particles from contaminating the surrounding environment while allowing necessary air exchange for the mixing operation

Inventive Principle:
Principle #39Inert atmosphere (Inert environment)

2Productivity

If air is allowed to circulate freely during the mixing process, then mixing efficiency is improved, but impurities from ambient air enter the vial contaminating the medication

Engineering Contradiction:
Improvemixing efficiencyVSAvoidambient air impurities
Core Design Contradiction:
ProductivityVSObject-generated harmful factors

Solution Approach 1:

The filter serves as a mediator in the air circulation system, permitting air flow to maintain mixing efficiency while simultaneously blocking impurities from ambient air from entering the vial and contaminating the medication

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

By implementing filtered air circulation, the system creates a protected atmosphere around the vial that allows efficient mixing operations while excluding harmful ambient impurities, thus maintaining medication purity

Inventive Principle:
Principle #39Inert atmosphere (Inert environment)

3Ease of operation

If a needle is used to pierce the elastomeric membrane stopper, then the syringe can be connected to the vial, but the needle must be disconnected afterward creating direct contact risks with the medication mixture

Engineering Contradiction:
Improvesyringe connectionVSAvoiddirect contact exposure
Core Design Contradiction:
Ease of operationVSObject-affected harmful factors

Solution Approach 1:

The filter assembly acts as an intermediary component that remains in place between the syringe and vial throughout the entire process. This eliminates the need to disconnect and reconnect needles, allowing syringe operations while the filter continuously protects against direct contact exposure to medication particles

Inventive Principle:
Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The device ensures a safe and secure preparation of the medication mixture by filtering out particles and impurities, preventing contamination of the nursing staff and ensuring the quality of the prepared infusion.

Implementation Method 1

comprising air filtration means... passing through the filtration means which will then retain, on the one hand during air outlet from the bottle, the particles of pure medicine not yet diluted and, on the other hand when air enters the bottle, impurities contained in the ambient air penetrating into the bottle

Methodology Applied
Scientific EffectFiltration: Filter (physical)

Data Source

PatentEP2262464B1Interface device for bottles designed to be perforated for the preparation of infused liquids
Publication Date: 2012.10.10 VYGON SA
  • EP2262464B1 patent drawingFigure 1~2
  • EP2262464B1 patent drawingFigure 3~5
  • EP2262464B1 patent drawingFigure 6~8

AI summary

Interface device (1) designed to connect a syringe to a perforable bottle (2) containing a drug, comprising a base (100) for connection to the perforable bottle, which connection base comprises air circulation means (101, 105, 108, 109) designed to allow air in and out of the perforable bottle, comprising air filtration means (109).