Interlocking Adhesion Sheet for Anastomotic Leakage Reduction

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Solution Overview

Problem

Existing methods for joining biological organs, such as anastomosis, may not sufficiently reduce the risk of anastomotic leakage due to varying tissue states in patients, despite using mechanical joining devices.

Innovation Solution

An adhesion promotion device with a sheet-shaped main body portion having distinct regions and an interlock portion, designed to promote tissue adhesion and secure the device between biological organs, reducing the risk of leakage by covering suture portions and preventing device displacement.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Strength

If a mechanical joining device is used for anastomosis, then the joining force between biological organs is improved, but the risk factors of anastomotic leakage cannot be sufficiently reduced due to varying tissue states

Engineering Contradiction:
Improvejoining forceVSAvoidanastomotic leakage risk
Core Design Contradiction:
StrengthVSReliability

Solution Approach 1:

The adhesion promotion device is divided into multiple functional regions: a first region with through-holes for tissue adhesion promotion, a second region for covering the suture portion, and an interlock portion for securing the device. This segmentation allows each region to perform its specific function optimally, addressing both joining strength and leakage prevention

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

Different regions of the device have different structural properties tailored to their specific functions. The first region has through-holes to promote adhesion at the tissue interface, while the second region is solid to cover and protect the suture portion. This local differentiation ensures that each area of the device optimally addresses the specific requirements of that location

Inventive Principle:
Principle #3Local quality

2Reliability

If a sheet-shaped adhesion promotion device is used, then tissue adhesion is promoted, but the device may fall out of the biological organ

Engineering Contradiction:
Improvetissue adhesion promotionVSAvoiddevice retention
Core Design Contradiction:
ReliabilityVSStability of the object's composition

Solution Approach 1:

The second region of the device is designed to cover and enclose the suture portion, creating a nested structure where the adhesion promotion device contains the suture. This nesting ensures that the device remains retained while maintaining its adhesion promotion function

Inventive Principle:
Principle #7Nested doll (Nesting)

Solution Approach 2:

The device combines multiple functions into a single integrated structure: adhesion promotion through the first region, suture coverage through the second region, and secure retention through the interlock portion. This merging ensures that adhesion promotion and device retention work together rather than in opposition

Inventive Principle:
Principle #5Merging (Combining)

3Reliability

If the second region is separated from the first region, then the device can cover the suture portion, but the structural complexity increases

Engineering Contradiction:
Improvesuture coverageVSAvoidregional separation
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The device is segmented into distinct regions (first region with through-holes, second region for coverage, and interlock portion) that are connected through the interlock structure. This segmentation provides functional differentiation while maintaining overall structural integrity through the interlocking mechanism

Inventive Principle:
Principle #1Segmentation

Data Source

PatentUS12514585B2Adhesion promotion device
Publication Date: 2026.01.06 TERUMO KK
  • US12514585B2 patent drawing
  • US12514585B2 patent drawing
  • US12514585B2 patent drawing

AI summary

An adhesion promotion device is disclosed, which is capable of reducing risk factors of an anastomotic leakage after surgery. The adhesion promotion device includes a sheet-shaped first region disposed between one joint target site and the other joint target site of biological organs to promote adhesion of a biological tissue, a second region provided inward of the first region and separated from the first region in a direction intersecting with a surface direction of the first region, and an interlock portion that interlocks the first region and the second region with each other.