Intestinal Barrier Sleeve Release via Dissolvable Body

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Solution Overview

Problem

Current diabetes treatment methods, such as gastric bypass surgery and intestinal bypass liners, are invasive, costly, and pose risks, while existing devices for intestinal barrier sleeve release systems are complex and difficult to operate, limiting their widespread application and accessibility.

Innovation Solution

An intestinal barrier sleeve release system guided by a gastroscope, featuring a tubular housing with a dissolvable release body and a push assembly, which separates intestinal tissues from food, improving insulin secretion and diabetes treatment with a simple structure, low manufacturing cost, and reduced risk of complications.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If gastric bypass surgery is performed to treat diabetes, then the treatment effectiveness is improved, but surgical risks and complications increase

Engineering Contradiction:
Improvetreatment effectivenessVSAvoidsurgical risks
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent replaces traditional surgical mechanical intervention (gastric bypass surgery) with a minimally invasive endoscopic delivery system. The intestinal barrier sleeve is delivered through the gastrointestinal tract using an endoscope and guidewire, avoiding external surgical incisions and reducing surgical risks while maintaining treatment effectiveness for diabetes and obesity.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent introduces an intestinal barrier sleeve as an intermediary device that creates a physical barrier in the duodenum. This sleeve acts as a mediator between food intake and nutrient absorption, allowing controlled passage of nutrients while preventing excessive calorie absorption, thereby treating obesity and diabetes without direct surgical modification of organs.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Reliability

If intestinal bypass liner is used to treat diabetes, then treatment effectiveness is improved, but device complexity and operational difficulty increase

Engineering Contradiction:
Improvetreatment effectivenessVSAvoiddevice structure
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The delivery system is segmented into distinct functional modules: an outer sheath for protection, an inner sheath for deployment, a push rod for advancement, and the intestinal barrier sleeve itself. This segmentation allows each component to perform its specific function independently, simplifying the overall operation and reducing the complexity of managing multiple simultaneous actions required by previous single-piece designs.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The intestinal barrier sleeve is pre-formed and sterilized before use, and the delivery system is pre-assembled with all components in place. The endoscopist simply needs to advance the system through the GI tract and deploy the sleeve, eliminating the need for complex intra-procedural assembly or multiple separate操作步骤, thereby reducing operational difficulty.

Inventive Principle:
Principle #10Preliminary action

3Reliability

If intestinal bypass liner is used to treat diabetes, then treatment effectiveness is improved, but manufacturing cost increases

Engineering Contradiction:
Improvetreatment effectivenessVSAvoidmanufacturing cost
Core Design Contradiction:
ReliabilityVSEase of manufacture

Solution Approach 1:

The intestinal barrier sleeve is constructed from thin, flexible biocompatible materials that can be manufactured using standard medical device fabrication techniques. The sleeve utilizes a simple tubular structure with radial expandability, avoiding complex multi-layer constructions or specialized materials, thereby reducing manufacturing costs while maintaining effectiveness for creating the intestinal barrier.

Inventive Principle:
Principle #30Flexible shells and thin films

4Object-affected harmful factors

If dissolvable release body is used in intestinal barrier sleeve release system, then surgical risks are reduced, but device complexity increases

Engineering Contradiction:
Improvesurgical risksVSAvoidrelease mechanism
Core Design Contradiction:
Object-affected harmful factorsVSDevice complexity

Solution Approach 1:

The release body is designed to change its physical state from solid to dissolved form through a parameter change (exposure to gastrointestinal fluids). This chemical/physical transformation automatically triggers the release mechanism, eliminating the need for complex mechanical actuators or controlled deployment systems. The dissolving property of the release body itself becomes the driving force for sleeve deployment, simplifying the overall mechanism.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system effectively treats type 2 diabetes and obesity with minimal pain and quick recovery, as the dissolvable release body is absorbed by the body, reducing surgical risks and promoting better quality of life without the need for dietary restrictions.

Implementation Method 1

The release body is disposed at the first opening, connected to one end of the tubular sleeve, and made of a material that is able to be dissolved and absorbed in human intestines

Methodology Applied
Scientific EffectDissolution and absorption: Solvation

Data Source

PatentEP3560463B1Membrane tube releaser for intestinal tract isolation
Publication Date: 2025.01.08 HANGZHOU TANGJI MEDICAL TECH CO LTD
  • EP3560463B1 patent drawingFigure 1
  • EP3560463B1 patent drawingFigure 2
  • EP3560463B1 patent drawingFigure 3~4

AI summary

Provided is a membrane tube releaser for intestinal tract isolation, comprising a tubular shell (1), with one end of the shell (1) being provided with a first opening (11), and the other end thereof being provided with a second opening (13), the shell being internally provided with a membrane tube (31) to be released and further comprising a release body (2), wherein same is arranged at the first opening (11), is connected to one end of the membrane tube (31), and is made of a material that can be digested and absorbed by the human intestinal tract; and an inner tube (41), a middle tube (42) and an outer tube (43) sheathed in sequence and able to move relative to each other, wherein a part of the inner tube (41) is located inside the shell (1) and is connected to the release body (2), a stopper piston (12) located in the shell (1) is fixedly sheathed outside one end of the middle tube (42), and the outer tube (43) is located outside the shell and has one end thereof fixedly connected to the second opening (13). The inner tube (4) and the middle tube (42) are operated to move in an axial direction, the release body (2) is separated from the shell (1), and the membrane tube (31) is detached from the shell and is released at a specified position in the human intestinal tract. The releaser is simple in structure, low in manufacturing cost, simple in operation, and strong in reliability, will not cause a wound when same is implanted into the human body, and causes no toxicity or side effects for the human body.