Automated Intestinal Wall Segmentation for Structural Damage Measurement

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Solution Overview

Problem

Current methods for measuring and monitoring structural damage in the small intestine, such as those caused by inflammatory bowel diseases, are time-consuming, require experienced radiologists, and have limited reproducibility, making it challenging for physicians to make informed treatment decisions.

Innovation Solution

An automated computer-automated method for segmenting image data of the small intestine using a computing device that generates three-dimensional structures of the outer and inner walls, allowing for precise measurement and comparison of structural damage across scans or between subjects.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If manual measurement methods are used by experienced radiologists, then measurement accuracy is improved, but time consumption and device complexity increase

Engineering Contradiction:
Improvestructural damage measurement accuracyVSAvoidtime consumption for measurement
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The system performs automated segmentation and measurement of intestinal structures using computer algorithms that process medical images independently, without requiring manual intervention by radiologists. The algorithm automatically identifies the intestinal lumen, segments the bowel wall, and calculates structural damage metrics, enabling the system to serve itself rather than relying on human operators for each measurement task.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The patent replaces the manual mechanical measurement process performed by radiologists with an automated computational system. Instead of human eyes visually assessing images and manually measuring structures, a computer-based algorithm processes the medical images, performs segmentation, and calculates measurements automatically, substituting the mechanical human measurement process with an automated digital system.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Measurement precision

If manual measurement methods are used by experienced radiologists, then measurement accuracy is improved, but operator dependency and reproducibility worsen

Engineering Contradiction:
Improvestructural damage measurement accuracyVSAvoidreproducibility of measurement
Core Design Contradiction:
Measurement precisionVSReliability

Solution Approach 1:

The system performs automated segmentation and measurement of intestinal structures using computer algorithms that process medical images independently, without requiring manual intervention by radiologists. The algorithm automatically identifies the intestinal lumen, segments the bowel wall, and calculates structural damage metrics, enabling the system to serve itself rather than relying on human operators for each measurement task.

Inventive Principle:
Principle #25Self-service

3Productivity

If automated segmentation is implemented, then productivity and reproducibility are improved, but measurement precision and complexity of implementation worsen

Engineering Contradiction:
Improvemeasurement efficiencyVSAvoidstructural damage measurement accuracy
Core Design Contradiction:
ProductivityVSMeasurement precision

Solution Approach 1:

The patent divides the complex task of intestinal assessment into distinct segmented components: first identifying the intestinal lumen, then segmenting the bowel wall into different layers, and finally measuring specific structural parameters. This segmentation approach allows the automated system to handle each component separately with specialized algorithms, improving both accuracy and efficiency while maintaining reproducibility across different patients and time points.

Inventive Principle:
Principle #1Segmentation

Data Source

PatentUS10918326B2Automated assessment of bowel damage in intestinal diseases
Publication Date: 2021.02.16 THE RGT UNIV OF MICHIGAN
  • US10918326B2 patent drawing
  • US10918326B2 patent drawing
  • US10918326B2 patent drawing

AI summary

A computer-automated method is presented for segmenting image data for an organ of a subject, where the organ is a tubular structure. The method includes: receiving image data representing a volume of the subject, such that the image data includes the organ; generating a centerline through the organ; determining location of an outer wall of the tube within the image data, where the location of the inner wall is determined using the centerline; determining location of an outer wall of the tube within the image data, where the location of the outer wall is determined using the inner wall; and computing a measure of the organ from the image data.