Intrabody Device for Controlled Venous Sclerosing Agent Administration

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Solution Overview

Problem

Current methods for administering sclerosing agents into veins face challenges such as dilution and harmful side effects due to limited concentration and foaming techniques, which are not effective for treating smaller veins and can cause blood clotting.

Innovation Solution

An intrabody device with multiple tubular ducts for controlled ejection and suction of sclerosing agents into and from the venous lumen, allowing precise administration and withdrawal to maintain a predefined space, using ejection and suction pressures and directions tailored to the vein characteristics.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If the concentration of sclerosing agent is increased to offset dilution, then treatment effectiveness is improved, but harmful effects are introduced

Engineering Contradiction:
Improvetreatment effectivenessVSAvoidharmful effects
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The device divides the venous lumen into multiple treatment zones using multiple tubular ducts positioned at different locations and angles. Each duct can deliver sclerosing agent to a specific segment of the vein wall, allowing localized treatment with lower concentrations while avoiding system-wide distribution and harmful effects

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The invention applies sclerosing agent locally directly to the venous wall through multiple targeted ducts rather than diffuse injection into the lumen. This local application ensures high concentration at the treatment site (venous wall) while minimizing overall agent quantity and preventing systemic harmful effects

Inventive Principle:
Principle #3Local quality

2Reliability

If foaming techniques are used to treat veins, then dilution effect is offset, but blood clotting is caused throughout the vascular system

Engineering Contradiction:
Improvetreatment effectivenessVSAvoidblood clotting
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The device extracts and removes excess sclerosing agent and foam from the venous lumen using suction ducts positioned near the injection sites. This extraction prevents the foam from traveling through the vascular system and causing widespread blood clotting, while maintaining local treatment effectiveness

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The invention converts the potentially harmful foam into a beneficial localized treatment by using the foam's expansion properties to push the sclerosing agent directly against the venous wall, then immediately removing the foam residue through suction to prevent systemic clotting

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

3Reliability

If sclerosing agent is injected into the vein, then the venous wall is treated, but the agent is rapidly diluted

Engineering Contradiction:
Improvetreatment effectivenessVSAvoidsclerosing agent concentration
Core Design Contradiction:
ReliabilityVSQuantity of substance

Solution Approach 1:

The device positions multiple tubular ducts in advance within the venous lumen at optimal locations and angles before injection. This preliminary positioning ensures that the sclerosing agent is delivered directly to targeted areas of the venous wall, preventing dilution by blood flow and maintaining effective concentration at the treatment site

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The tubular ducts act as intermediaries between the sclerosing agent reservoir and the venous wall. These ducts guide and direct the agent along controlled pathways, preventing premature mixing with blood and maintaining concentration integrity until the agent reaches the target tissue

Inventive Principle:
Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables effective treatment of veins with lower sclerosing agent concentrations, reducing the risk of dilution and blood clotting by ensuring the agent contacts the venous wall directly, while allowing for higher concentrations to be used safely, even in smaller veins.

Implementation Method 1

an ejection force source connected to at least one tubular duct and configured for applying an ejection force for conducing therethrough a liquid medical substance to the at least one outlet for administering the liquid medical substance at an ejection pressure, quantity and direction

Methodology Applied
Scientific EffectPressure gradient: Pressure Gradient

Implementation Method 2

a suction force source connected to at least one tubular duct and configured for applying a suction force for withdrawing therethrough a residue of the liquid medical substance from the at least one inlet in a suction pressure, quantity and direction

Methodology Applied
Scientific EffectSuction: Suction

Data Source

PatentEP2259831B1Device for liquid medical substance venous administration
Publication Date: 2020.07.22 V V T MED
  • EP2259831B1 patent drawingFigure 1
  • EP2259831B1 patent drawingFigure 2~3D
  • EP2259831B1 patent drawingFigure 4A~4B

AI summary

A method for administering a liquid medical substance in a vein. The method comprises inserting a plurality of tubular ducts into a target venous lumen, conducting a liquid medical substance via at least one of the plurality of tubular ducts (106, 215, 419, 602) for the administering thereof toward a venous wall (110, 410) at the target venous lumen in an ejection pressure, quantity and direction, and withdrawing a residue of the liquid medical substance from the target venous lumen, in a suction pressure, quantity and direction, for the conducting thereof via at least one different of the plurality of tubular ducts (130, 240, 400). A relation between the ejection pressure, quantity and direction and the suction pressure, quantity and direction limits the extent of the administering within the venous lumen to a predefined space.