Intracranial Hemodynamic Parameter Determination via CT Imaging

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Solution Overview

Problem

Current methods for determining intracranial hemodynamic parameters face challenges in accurately simulating boundary conditions of blood vessels, which hinders the efficiency and effectiveness of computational fluid dynamics calculations.

Innovation Solution

A method and system that utilize CT angiographic and perfusion imaging data to determine three-dimensional vessel models and boundary conditions of inlets and outlets, enabling the calculation of intracranial hemodynamic parameters such as blood pressure, flow velocity, and wall shear stress.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If computational fluid dynamics is used to calculate hemodynamic parameters, then measurement precision is improved, but device complexity and calculation time increase

Engineering Contradiction:
Improvehemodynamic parameter accuracyVSAvoidcalculation system complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent applies preliminary action by pre-determining boundary conditions from CT imaging data before performing computational fluid dynamics calculations. The method extracts vascular geometry and hemodynamic parameters from medical images in advance, prepares boundary condition models, and sets up the computational framework beforehand. This preliminary preparation reduces the complexity and time required during the actual CFD simulation while maintaining high measurement precision for hemodynamic parameters.

Inventive Principle:
Principle #10Preliminary action

2Measurement precision

If complex boundary conditions are simulated, then measurement precision is improved, but loss of time increases

Engineering Contradiction:
Improveboundary condition accuracyVSAvoidcalculation time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent applies copying by creating simplified boundary condition models that replicate the essential characteristics of complex physiological conditions. Instead of simulating the full complexity of actual blood flow boundary conditions, the method generates representative boundary condition models from CT imaging data that capture the key hemodynamic features. This copying approach maintains measurement precision for critical parameters while significantly reducing calculation time by avoiding unnecessary computational complexity.

Inventive Principle:
Principle #26Copying

3Measurement precision

If detailed three-dimensional vessel models are created, then measurement precision is improved, but device complexity increases

Engineering Contradiction:
Improvevessel model accuracyVSAvoidmodeling system complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent applies mechanics substitution by replacing complex manual or mechanical modeling processes with automated image processing and computational methods. The system uses CT angiographic and perfusion imaging data to automatically generate three-dimensional vessel models through computational algorithms rather than traditional mechanical or manual modeling techniques. This substitution maintains high measurement precision for vessel geometry while reducing the complexity of the modeling system by leveraging automated data processing and reconstruction algorithms.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Data Source

PatentUS20230215584A1Method and system for determining intracranial hemodynamic parameter
Publication Date: 2023.07.06 SHANGHAI UNITED IMAGING HEALTHCARE
  • US20230215584A1 patent drawing
  • US20230215584A1 patent drawing
  • US20230215584A1 patent drawing

AI summary

A method for determining an intracranial hemodynamic parameter according to embodiments of the present disclosure is provided, which includes determining a three-dimensional a model of a blood vessel based on CT angiographic data, and determining at least one of a boundary condition of each inlet or a boundary condition of each outlet in the three-dimensional vessel model based on CT perfusion imaging data and CT angiographic data.