Intraocular Camera for Retinal Prostheses Using Curved Substrates

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Current retinal prostheses face challenges such as difficulty in integrating photosensitive elements on curved substrates, fragile retinal tissue damage, heat dissipation issues, and the need for external cameras that cause disorientation due to their size and power consumption.

Innovation Solution

An intraocular camera with a compact optical system, designed to work with the corneal lens, providing images directly to a microstimulator array within the eye, using a biocompatible housing and haptic elements for stabilization, with antireflection coatings and power management to reduce heat and mass, allowing for chronic implantation and natural foveation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of manufacture

If photosensitive elements are incorporated within the microstimulator array, then the existing corneal lens and crystalline lens can be used for image formation, but the planar substrate becomes increasingly difficult to implant as the array size increases due to the curved retinal surface

Engineering Contradiction:
Improveintegration of photosensitive elementsVSAvoidcompatibility with curved retinal surface
Core Design Contradiction:
Ease of manufactureVSAdaptability or versatility

Solution Approach 1:

The patent transitions from a planar substrate to a curved substrate that conforms to the retinal surface. The microstimulator array is fabricated on a curved surface that matches the curvature of the retina, allowing the array to adapt to the anatomical geometry of the eye while maintaining the integration of photosensitive elements with the existing lens system.

Inventive Principle:
Principle #14Spheroidality (Curvature)

2Device complexity

If photosensitive elements are incorporated within the microstimulator array, then image capture is integrated, but the fragile retinal tissue is easily damaged by the proximal implantation of devices with hard edges

Engineering Contradiction:
Improveintegrated photostimulator arrayVSAvoiddamage to retinal tissue
Core Design Contradiction:
Device complexityVSObject-affected harmful factors

Solution Approach 1:

The patent employs a flexible, thin-film substrate that can conform to the retinal surface without rigid edges. This flexible substrate reduces mechanical stress and damage risk to the fragile retinal tissue while maintaining the integrated structure of photosensitive elements and stimulation electrodes.

Inventive Principle:
Principle #30Flexible shells and thin films

3Device complexity

If photosensitive elements are incorporated without associated amplification, then the structure is simpler, but the signals are not directly appropriate for localized electrical stimulation of the inner or outer layers of the retina

Engineering Contradiction:
Improvestructure of photosensitive elementsVSAvoidsignal suitability for retinal stimulation
Core Design Contradiction:
Device complexityVSEase of operation

Solution Approach 1:

The patent combines photosensitive elements, signal amplification circuitry, and stimulation electrode array into a single integrated microstimulator device. The amplification circuitry is fabricated directly on the same substrate as the photosensitive elements, enabling signal processing and stimulation delivery within the same implant without requiring separate components.

Inventive Principle:
Principle #5Merging (Combining)

4Productivity

If photosensitive elements and associated circuitry are incorporated within the microstimulator array, then space is utilized, but as the array is scaled up to higher densities, the available space is increasingly required for stimulation electrodes and interconnection wiring, leaving little if any space for photosensitive elements

Engineering Contradiction:
Improvedensity of microstimulator arrayVSAvoidspace for photosensitive elements
Core Design Contradiction:
ProductivityVSArea of stationary object

Solution Approach 1:

The patent transitions from a two-dimensional planar layout to a three-dimensional integrated structure. By fabricating circuitry and photosensitive elements in multiple layers on the curved substrate, the design accommodates higher densities of both stimulation electrodes and photosensitive elements without sacrificing space for either function.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

5Device complexity

If photosensitive elements and associated amplifiers are incorporated within the microstimulator array, then image processing is integrated, but an additional source of heat dissipation is placed directly in contact with the thermally-sensitive retina

Engineering Contradiction:
Improveintegration of signal processingVSAvoidheat dissipation near retina
Core Design Contradiction:
Device complexityVSTemperature

Solution Approach 1:

The use of a thin-film substrate provides thermal isolation between the active electronics and the retinal tissue. The thin film acts as a thermal barrier that reduces heat transfer to the retina while still allowing optical transmission and electrical functionality.

Inventive Principle:
Principle #30Flexible shells and thin films

6Ease of operation

If an external camera is used to supply images, then the microstimulator array can receive visual input, but the patient must employ rapid head motion to search the visual field, leading to disorientation, dizziness, and nausea

Engineering Contradiction:
Improvevisual field coverageVSAvoiddisorientation and dizziness
Core Design Contradiction:
Ease of operationVSObject-affected harmful factors

Solution Approach 1:

The patent extracts the camera function from an external device and integrates it directly into the intraocular implant. This eliminates the need for external cameras and rapid head motions, as the camera is now positioned within the eye to capture images naturally aligned with the patient's visual axis.

Inventive Principle:
Principle #2Taking out (Extraction)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables natural foveation, expanded depth of field, and enhanced patient acceptability by providing continuous video streams to the microstimulator array, reducing heat and mass within the eye, and eliminating the need for external cameras, thus improving image clarity and reducing disorientation.

Implementation Method 1

an optical imaging system, which includes a set of optical elements configured to be used in conjunction with the corneal lens or refracting surface for forming images on an image sensor array

Methodology Applied
Scientific EffectRefraction: Refraction

Implementation Method 2

with antireflection coatings

Methodology Applied
Scientific EffectReflection: Reflection

Data Source

PatentUS8197539B2Intraocular camera for retinal prostheses
Publication Date: 2012.06.12 UNIV OF SOUTHERN CALIFORNIA
  • US8197539B2 patent drawing
  • US8197539B2 patent drawing
  • US8197539B2 patent drawing

AI summary

An intraocular camera for retinal prostheses may include an optical imaging system comprising a set of optical elements for forming an image of the external world on an image sensor array, wherein the optical elements and the image sensor array may be enclosed in an implantable biocompatible housing that may employ haptic elements for stabilization within the eye. The set of optical elements may be designed to have a short focal length and to provide adequate resolution images that can be transformed into a set of stimulation signals applied to a pixellated microstimulator array. Transmission of the signals from the intraocular camera to a microstimulator driver circuit may be accomplished either by a wired or wireless communication device. Power and control signals may be provided to the intraocular camera by a wired or wireless communication device, or optically by means of ambient illumination or an optical beam.