Retrievable Intrasaccular Mesh Occlusion for Aneurysm Neck Sealing
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Current occlusion devices for treating aneurysms, particularly neurovascular aneurysms, face challenges such as embolic material migration, irreversible occlusion of parent arteries, and the need for additional anchoring mechanisms, which can lead to complications like stroke and increased trauma to the patient.
Innovation Solution
An occlusion device using a minimum amount of fully-retrievable, low-profile resilient mesh material that is oversized to conform to the aneurysm, eliminating the need for additional anchoring and minimizing clot emboli formation, with a marker to seal the aneurysm neck and promote clot formation.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If traditional occlusion devices are used to treat aneurysms, then the aneurysm can be occluded, but embolic material may migrate and cause stroke
Solution Approach 1:
The device is divided into distinct functional segments: a delivery catheter for minimally invasive insertion, an expandable occlusion body for sealing the aneurysm, and a retrieval mechanism. This segmentation allows the occlusion function to be separated from the delivery and retrieval functions, enabling safe deployment and removal without embolic material migration.
Solution Approach 2:
The occlusion device is designed to be fully retrievable if needed. The expandable body can be collapsed back into the delivery catheter and removed from the patient's vasculature, allowing recovery of the device should complications arise or the procedure need to be reversed, thus preventing stroke from embolic material.
2Stability of the object's composition
If anchoring mechanisms are added to secure the occlusion device, then the device stability improves, but trauma to the patient increases
Solution Approach 1:
The occlusion device achieves stability through self-expansion within the aneurysm sac. The expandable body automatically engages with the aneurysm walls through its elastic recovery force, eliminating the need for separate anchoring mechanisms that would require additional holes or attachments, thus reducing patient trauma while maintaining device stability.
3Reliability
If more material is used in the occlusion device, then the occlusion effectiveness increases, but the device complexity and trauma increase
Solution Approach 1:
The occlusion device uses a thin-walled expandable body made of flexible material that can be collapsed into a compact form for delivery through a small catheter. When expanded, this thin film structure provides sufficient occlusion effectiveness by sealing the aneurysm sac, avoiding the need for large amounts of material while reducing device complexity and delivery trauma.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The device effectively seals the aneurysm neck, reduces the risk of clot emboli, and minimizes the need for anti-coagulation therapy, while being fully retrievable and adaptable to various aneurysm morphologies.
Implementation Method 1
a low profile resilient mesh body... capable of conforming to aneurysm walls
Data Source
AI summary
Provided herein is an occlusion device for intrasaccular implantation and/or vascular occlusion comprising: (a) a substantially solid marker having a proximal end, and a distal end; and (b) a low profile resilient mesh body attached to the distal end of the marker, the body having a delivery shape and a deployed shape capable of conforming to aneurysm walls; wherein the body has a diameter greater than a diameter of an aneurysm to be treated. Also provided herein is a kit comprising the occlusion device disclosed herein and a means for delivery thereof. Methods of manufacture and use of the occlusion device disclosed herein are also disclosed.