Intravaginal Device Using Semi-Permeable Elastomer for Lubricant Diffusion

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Solution Overview

Problem

Current treatments for vaginal dryness, such as lubricating creams and hormone replacement therapy, are either messy, provide temporary relief, or carry risks like endometrial hyperplasia and increased risk of heart attacks, strokes, and breast cancer.

Innovation Solution

Intravaginal devices with a hydrophilic, semi-permeable elastomer segment that slowly releases aqueous lubricants, including water, hypo-osmotic, iso-osmotic, and hyper-osmotic solutions, directly to the vaginal tissues, providing sustained moisture and pH maintenance without systemic absorption.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Duration of action of moving object

If lubricating creams or jellies are used, then vaginal moisture is increased, but the treatment is messy and provides only short-lived temporary relief

Engineering Contradiction:
Improveduration of moisture reliefVSAvoidease of application
Core Design Contradiction:
Duration of action of moving objectVSEase of operation

Solution Approach 1:

The device segments the lubricant delivery system into a reservoir compartment and a release mechanism, allowing controlled dispensing of lubricant only when needed, thereby extending duration of action while maintaining ease of operation through simple activation

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent introduces an intermediary release mechanism (such as a rupture membrane or valve system) between the lubricant reservoir and the vaginal environment, enabling controlled delivery that extends duration of action while avoiding the messiness of direct application

Inventive Principle:
Principle #24Intermediary (Mediator)

2Duration of action of moving object

If topical estrogen creams are used, then vaginal moisture is increased, but systemic absorption may occur causing endometrial stimulation and potential carcinoma

Engineering Contradiction:
Improveduration of moisture reliefVSAvoidsystemic absorption risks
Core Design Contradiction:
Duration of action of moving objectVSObject-affected harmful factors

Solution Approach 1:

The patent extracts the harmful estrogen component from the treatment while retaining the beneficial lubricating effect, using a purely mechanical or physical lubricant delivery system that provides moisture without systemic absorption risks

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The device uses a disposable intravaginal insert that delivers lubricant locally without systemic effects, eliminating the harmful long-term consequences of estrogen therapy while providing sufficient duration of action for its intended use period

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

3Reliability

If hormone replacement therapy is used, then vaginal dryness and atrophy are relieved, but risk of heart attacks, stroke, blood clots, and breast cancer increases

Engineering Contradiction:
Improveeffectiveness in relieving vaginal drynessVSAvoidrisk of cardiovascular events and cancer
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent extracts the therapeutic lubricating function from hormone-based treatments, providing a non-hormonal alternative that maintains reliability for relieving vaginal dryness while eliminating the harmful cardiovascular and oncological risks associated with HRT

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The device introduces a physical intermediary (the intravaginal device itself) that delivers lubricant locally without requiring systemic hormone circulation, thereby maintaining therapeutic effectiveness while avoiding the harmful systemic effects of hormone replacement therapy

Inventive Principle:
Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The devices offer non-irritating, hormone-free, long-lasting relief from vaginal dryness, irritation, and discomfort, promoting a normal vaginal environment with controlled release of lubricants for up to 30 days.

Implementation Method 1

The first segment is configured to deliver the contents of the lumen to the outer surface by diffusion

Methodology Applied
Scientific EffectDiffusion: Diffusion

Implementation Method 2

The first segment includes a hydrophilic, semi-permeable elastomer

Methodology Applied
Scientific EffectPermeation: Permeation

Data Source

PatentEP2637730B1Intravaginal devices for controlled delivery of lubricants
Publication Date: 2021.08.25 UNIV OF UTAH RES FOUND
  • EP2637730B1 patent drawingFigure 1~2C
  • EP2637730B1 patent drawingFigure 2D~2F
  • EP2637730B1 patent drawingFigure 3~5

AI summary

The present technology provides intravaginal devices designed to deliver lubricants to the vagina for a sustained period of time. The intravaginal devices include a first segment comprising an outer surface and a lumen containing a lubricant, wherein the first segment is configured to deliver the contents of the lumen to the outer surface, and the first segment comprises a polymer selected from the group consisting of a hydrophilic, semi-permeable elastomer and a hydrophobic elastomer. The lubricant may be an aqueous lubricant. The present technology further provides an intravaginal device including a solid first segment that includes a hydrophilic semi-permeable elastomer, an outer surface and an aqueous lubricant, wherein the first segment is configured to deliver the aqueous lubricant to the outer surface.