Intravascular Imaging Probe Co-Registration
Solution Overview
Problem
Current high-resolution imaging technologies, such as combined ultrasound and optical coherence tomography, face challenges in accurately co-registering images due to non-uniform rotational distortion and displacement of imaging probes within the body, limiting their effectiveness in minimally invasive procedures like intravascular imaging.
Innovation Solution
The development of an imaging probe that combines acoustic and optical imaging means, allowing for precise co-registration of images by aligning the ultrasound and optical imaging elements along the same axis and using a scanning mechanism that adjusts rotation velocity to maintain accurate alignment during scanning, enabling simultaneous imaging and therapeutic energy delivery.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Object-affected harmful factors
If the imaging probe is inserted into the body for minimally invasive procedures, then the invasiveness is reduced, but the accuracy of image co-registration deteriorates due to non-uniform rotational distortion and probe displacement
Solution Approach 1:
The system employs feedback mechanisms by continuously monitoring the rotational position and orientation of the imaging probe using sensors (e.g., encoders, gyroscopes) and using this information to dynamically adjust and correct the co-registration of images from multiple modalities, thereby maintaining accuracy despite probe movement or distortion during minimally invasive procedures
Solution Approach 2:
The patent introduces intermediary components such as reference markers, alignment fiducials, or intermediate coordinate transformation systems that facilitate accurate co-registration between ultrasound and optical images by providing a common reference framework, even when the probe undergoes non-uniform rotation or displacement
2Ease of manufacture
If the ultrasound and optical imaging elements are positioned at different locations along the probe, then the structural design is simplified, but the accuracy of image co-registration deteriorates
Solution Approach 1:
The system compensates for spatial separation between imaging elements by introducing temporal dimension (synchronized acquisition timing) and computational dimension (software-based co-registration algorithms) to achieve accurate image alignment despite physical separation of transducers along the probe
3Productivity
If the rotation velocity is increased to improve scanning speed, then the productivity is improved, but the geometric precision of images deteriorates due to non-uniform rotational distortion
Solution Approach 1:
The system transitions from static to dynamic control by continuously adjusting rotation velocity based on real-time feedback from encoders and position sensors, allowing the probe to maintain optimal scanning speed while dynamically compensating for non-uniform rotational distortion through active control algorithms that adjust imaging parameters according to actual rotational state
4Adaptability or versatility
If the imaging probe is designed to deliver therapeutic energy, then the versatility is improved, but the device complexity increases
Solution Approach 1:
The patent combines multiple functions (imaging and therapy) into a single integrated probe by merging ultrasound transducers, optical fibers, and therapeutic energy delivery mechanisms (e.g., laser fibers, electrodes) into one device, allowing simultaneous or sequential imaging and treatment while reducing the need for multiple separate instruments
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This solution enhances the accuracy of image co-registration and geometric precision, improving the ability to assess vascular structures and deliver therapeutic energy effectively, particularly in intravascular and other minimally invasive medical procedures.
Implementation Method 1
an ultrasound transducer emitting and receiving reflected ultrasound imaging energy signals
Implementation Method 2
an optical emitter/collector including light directing and receiving means associated with a distal end of a fiber optic for directing light imaging energy out of a distal end of the fiber optic and receiving reflected light imaging energy signals
Data Source
AI summary
The present invention provides an imaging probe for imaging mammalian tissues and structures using high resolution imaging, including high frequency ultrasound and optical coherence tomography. The imaging probes structures using high resolution imaging use combined high frequency ultrasound (IVUS) and optical imaging methods such as optical coherence tomography (OCT) and to accurate co-registering of images obtained from ultrasound image signals and optical image signals during scanning a region of interest.