Intravascular Pump Integrated Lead Troughs Thrombosis

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Solution Overview

Problem

Existing intravascular blood pumps face challenges such as limited size due to integrated motors, thrombosis and hemolysis from stationary inducers, and high crossing profiles due to electric leads, which hinder efficient blood flow and delivery through the heart.

Innovation Solution

The design incorporates an expandable housing region with integrated lead troughs to reduce profile and optimize blood flow, using a flexible and non-expandable impeller housing that maintains constant diameter during delivery, and integrates electrical leads within the housing to minimize profile and prevent thrombosis.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Length of moving object

If electric leads are integrated into the pump housing, then the crossing profile is reduced, but the risk of thrombosis increases

Engineering Contradiction:
Improvecrossing profileVSAvoidthrombosis risk
Core Design Contradiction:
Length of moving objectVSObject-affected harmful factors

Solution Approach 1:

The electrical leads are merged with the pump housing structure by integrating them into lead troughs formed in the housing wall. This combination reduces the overall crossing profile while the insulating coating on the leads prevents thrombosis by creating a non-thrombogenic barrier between the leads and blood.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

An insulating coating is introduced as an intermediary layer between the electrical leads and the blood. This coating serves as a mediator that prevents direct contact between the metallic leads and blood, thereby eliminating thrombosis risk while allowing the leads to be integrated into the housing structure.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Productivity

If the housing is made expandable to optimize blood flow, then blood flow efficiency improves, but the device complexity increases

Engineering Contradiction:
Improveblood flow efficiencyVSAvoidhousing structure complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The housing is designed with an expandable region that can dynamically change its diameter. The housing includes a non-expandable region with a first diameter and an expandable region with a second diameter larger than the first diameter, allowing the housing to adapt its configuration to optimize blood flow while maintaining structural integrity through the lead troughs.

Inventive Principle:
Principle #15Dynamics

3Reliability

If the impeller housing maintains constant diameter during delivery, then delivery safety improves, but the ability to expand for optimal blood flow is limited

Engineering Contradiction:
Improvedelivery safetyVSAvoidblood flow efficiency
Core Design Contradiction:
ReliabilityVSProductivity

Solution Approach 1:

The housing is segmented into distinct functional regions: a non-expandable region that maintains constant diameter during delivery to ensure safety, and an expandable region that can increase in diameter to optimize blood flow. The lead troughs are specifically formed in the non-expandable region to maintain structural stability during the delivery process.

Inventive Principle:
Principle #1Segmentation

Data Source

PatentEP3793674B1Intravascular pump with integrated isolated conductor(s) and methods thereof
Publication Date: 2024.10.16 CARDIOVASCULAR SYSTEMS INC
  • EP3793674B1 patent drawingFigure 1
  • EP3793674B1 patent drawingFigure 2~3
  • EP3793674B1 patent drawingFigure 4

AI summary

The present invention provides an intravascular blood pump comprising a housing region that may be expandable, wherein the housing region comprises a series of troughs extending along at least a portion of the length of the housing region, wherein the integrated lead trough(s) may be defined by or within the housing region and wherein each adjacent pair of troughs are separated by an insulated spacing gap and may be covered to form insulated conduits. The integrated lead trough(s) may be configured to receive one or more electrical leads therein.