Intravitreal Syringe Priming and Retraction for Safe Dosing
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Solution Overview
Problem
Existing administration devices for intravitreal injection lack safety, ease of use, and precise dosing, particularly for intravitreal administration of fluids or drugs.
Innovation Solution
An administration device with a pre-filled syringe housed within a protective mechanism, featuring a separate priming device and actuation mechanism that ensures safe handling and accurate dosing, allowing the syringe and needle to be fully retracted after use, with a blocking mechanism to prevent unintended dispensing during priming.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If a separate priming device is introduced to enable priming without actuating the syringe, then ease of operation is improved, but device complexity increases
Solution Approach 1:
The device is divided into functionally independent components: a separate priming device (10) for priming the syringe and an actuation mechanism (9) for dispensing the fluid. This segmentation allows priming to be performed without accidentally actuating the syringe, improving ease of operation while managing complexity through clear functional separation.
2Reliability
If a blocking device is added to prevent unintended dispensing during priming, then reliability is improved, but device complexity increases
Solution Approach 1:
The blocking device (12) is positioned to prevent the piston from moving beyond the priming position before the priming operation is complete. This preliminary blocking action prevents unintended fluid dispensing during priming, enhancing safety while adding only minimal structural complexity.
3Reliability
If the syringe and needle are designed to be fully retracted into the housing after use, then safety is improved, but ease of operation worsens due to additional retraction mechanism
Solution Approach 1:
The actuation mechanism (9) performs multiple functions in sequence: it actuates the piston to dispense fluid, then automatically retracts the syringe and needle into the housing. By merging these functions into a single mechanism, safety is improved without significantly increasing operational complexity.
4Ease of operation
If the actuation mechanism is configured to move the syringe relative to the housing, then ease of operation is improved, but device complexity increases
Solution Approach 1:
The actuation mechanism (9) is designed as a multi-functional component that can move the syringe relative to the housing, actuate the piston, and retract the needle. This universal mechanism improves ease of operation by consolidating multiple functions into one system, managing complexity through functional integration.
Data Source
AI summary
An administration device for in particular intravitreal administration of a fluid, the administration device having a preferably pre-filled syringe and an actuation mechanism for actuating the syringe. The administration device preferably includes a priming device, in particular in addition to the actuation mechanism. It is preferably prevented that the priming device be advanced beyond a defined end position. The syringe can preferably be moved within a housing of the administration device and/or positioned completely inside the housing.