Intraocular Lens Design for Spherical Aberration Correction

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Solution Overview

Problem

Current intraocular lens (IOL) designs fail to effectively address spherical aberration, particularly in cataract and presbyopic patients, as they rely on simplified models that do not accurately account for the optical properties of the crystalline lens, leading to suboptimal imaging quality.

Innovation Solution

The method involves designing IOLs by considering the optical properties of the crystalline lens separately, using measurable parameters like optical power and conic constant, and focusing on third-order aberrations to minimize spherical aberration, with the posterior chamber depth being a critical factor for shape fine-tuning, allowing for customization to correct aberrations on either the anterior or posterior surface.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of manufacture

If simplified two-lens eye models are used for IOL design, then design process is simplified and manufacturing is easier, but spherical aberration correction is insufficient and imaging quality deteriorates

Engineering Contradiction:
ImproveIOL design and manufacturing simplicityVSAvoidspherical aberration correction accuracy
Core Design Contradiction:
Ease of manufactureVSManufacturing precision

Solution Approach 1:

The patent segments the crystalline lens into multiple zones (central, intermediate, peripheral) with different optical properties. Each zone is assigned specific refractive indices and aberration contributions, allowing independent optimization of spherical aberration correction while maintaining manufacturing feasibility through standardized zonal structures.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent applies local quality by assigning different refractive indices to different radial zones of the crystalline lens model. The central zone has one refractive index while peripheral zones have different indices, enabling localized correction of spherical aberration without requiring complex global redesign of the entire IOL manufacturing process.

Inventive Principle:
Principle #3Local quality

2Measurement precision

If anatomically-accurate eye models are used for IOL design, then optical performance estimation is more accurate, but implementation complexity increases significantly

Engineering Contradiction:
Improveoptical performance estimation accuracyVSAvoideye model implementation complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent transforms the complex anatomically-accurate eye model into a simplified analytical model by changing key parameters: representing the crystalline lens as a multi-zonal system with specific refractive indices, defining fixed geometric relationships between optical elements, and using standardized aberration coefficients. This parameter transformation maintains optical performance accuracy while dramatically reducing implementation complexity.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent extracts only the essential optical properties from the complex anatomically-accurate eye model, separating the crystalline lens into distinct functional zones with specific refractive characteristics. By taking out only the critical parameters (refractive indices, zone boundaries, aberration contributions) needed for spherical aberration correction, the model achieves accurate optical performance estimation without unnecessary anatomical details.

Inventive Principle:
Principle #2Taking out (Extraction)

3Productivity

If conventional IOL designs are used, then manufacturing is straightforward, but spherical aberration is not effectively addressed leading to suboptimal imaging quality

Engineering Contradiction:
ImproveIOL manufacturing efficiencyVSAvoidimaging quality
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The patent applies preliminary action by pre-calculating the optimal conic constants and refractive index distributions for the multi-zonal crystalline lens model before IOL manufacturing. The spherical aberration correction parameters are determined in advance through optical modeling, allowing standard manufacturing processes to produce IOLs with optimized imaging quality without requiring complex post-manufacturing adjustments.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach enables the production of IOLs that significantly reduce spherical aberration, improving imaging quality for both cataract and presbyopic patients by accurately calculating the conic constant needed to minimize aberration, using biometric data and software integration for efficient and fast customization.

Implementation Method 1

The cornea with its refractive power of about 40 dpt contributes the main part of the refractive power of the eye... the crystalline lens provides the optical fine tuning... Due to the difference between the refractive index of air and of the cornea (nc ≈ 1.376)

Methodology Applied
Scientific EffectRefraction: Refraction

Data Source

PatentEP2442752B1Intra ocular lens
Publication Date: 2020.04.22 OCULENTIS HOLDING BV
  • EP2442752B1 patent drawingFigure 1~2
  • EP2442752B1 patent drawingFigure 3~5
  • EP2442752B1 patent drawingFigure 6~7

AI summary

The invention relates to a intra lens (1) comprising a posterior surface and an anterior surface, said posterior surface having a curvature which is optimised for providing a minimal spherical aberration, wherein said curvature is optimized using the posterior chamber depth of an eye in which the IOL is to be inserted.