Scanning Aperture Ion Beam Modulator for Parallel Proton Therapy

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Solution Overview

Problem

Current proton therapy systems face limitations in treatment speed and precision due to the complexity of techniques, which often require custom compensators and result in uneven dose placement and reduced conformity of radiation to the tumor, especially with strong asymmetry of the Bragg peak of protons.

Innovation Solution

A beam modulator that converts an area beam into multiple independent pencil beams, allowing simultaneous control of intensity and energy of each beam, reducing the need for custom compensators and enabling faster treatment by using shutter pairs to control the ion beam's intensity and energy independently.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Manufacturing precision

If a scanning pencil beam approach is used to treat the tumor, then manufacturing precision of dose placement is improved, but productivity is worsened due to successive exposures required to treat the entire tumor volume

Engineering Contradiction:
Improvedose placement precisionVSAvoidtreatment speed
Core Design Contradiction:
Manufacturing precisionVSProductivity

Solution Approach 1:

The invention segments the tumor volume into multiple slices along the beam axis, with each shutter pair treating one slice. Multiple shutter pairs operate simultaneously to treat multiple slices in parallel, converting the sequential pencil beam approach into a parallel area beam approach that maintains precision while dramatically increasing treatment speed

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The invention adds the longitudinal dimension to the treatment by using multiple shutter pairs at different positions along the beam axis. Each shutter pair controls a specific slice, enabling simultaneous treatment of multiple slices in the longitudinal direction, thus transforming the treatment from a one-dimensional sequential process to a three-dimensional parallel process

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

2Productivity

If the proton beam is expanded to treat the entire tumor at once, then productivity is improved, but manufacturing precision is worsened due to reduced conformity and uneven dose placement

Engineering Contradiction:
Improvetreatment speedVSAvoiddose placement precision
Core Design Contradiction:
ProductivityVSManufacturing precision

Solution Approach 1:

The invention segments the expanded area beam into multiple independent pencil beams, with each shutter pair controlling a specific slice. This segmentation allows each slice to be treated with precise dose control while maintaining high productivity through parallel treatment of multiple slices simultaneously

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The invention applies local quality control by allowing each shutter pair to independently adjust the energy and intensity of its corresponding pencil beam slice. This enables precise tailoring of the Bragg peak depth and dose distribution for each local slice, ensuring optimal dose conformity throughout the entire tumor volume

Inventive Principle:
Principle #3Local quality

3Manufacturing precision

If multiple angles are used to improve tumor conformity, then manufacturing precision is improved, but device complexity is worsened due to the need for complex modulation systems

Engineering Contradiction:
Improvetumor conformityVSAvoidmodulation system complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The invention creates a universal modulation system where the same shutter pair mechanism can treat multiple slices at any gantry angle. The system is angle-independent, meaning the same hardware configuration can treat tumors from any angular position, eliminating the need for angle-specific modulation systems and reducing overall device complexity

Inventive Principle:
Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach significantly increases treatment speed, allows for precise control of radiation dose distribution, and reduces the risk of uneven dose placement, enabling more efficient and accurate tumor irradiation with the ability to treat at multiple angles.

Implementation Method 1

An area beam of ions is directed along an axis and having a longitudinal and latitudinal extent in cross-section. The area beam is controllably occluded with a set of longitudinally opposed latitudinally adjacent shutter pairs

Methodology Applied
Scientific EffectIon beam: Ion Beam

Implementation Method 2

The dose deposited by a proton beam is not uniform along the entrance path of the beam, but rises substantially to a 'Bragg peak' near a point where the proton beam stops within the tissue. The shutters may control either or both the intensity and energy of the ion beams

Methodology Applied
Scientific EffectBragg peak:

Data Source

PatentUS7977648B2Scanning aperture ion beam modulator
Publication Date: 2011.07.12 WISCONSIN ALUMNI RES FOUND
  • US7977648B2 patent drawing
  • US7977648B2 patent drawing
  • US7977648B2 patent drawing

AI summary

A modulator for ions such as protons employs multiple shutter pairs to create independently movable apertures effecting a multiple pencil beam treatment of the patient thereby increasing treatment speed by eliminating the need for a custom compensator.