Ion Analyzer Signal Segmentation for Mass Resolution

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Solution Overview

Problem

Existing methods for analyzing image-charge/current signals from ion traps face challenges in accurately determining the dynamics of periodic components, particularly in non-harmonic signals, due to overlapping harmonics and the computational complexity of time-frequency analysis techniques like Short Time Fourier Transforms.

Innovation Solution

A method that converts a one-dimensional image-charge/current signal into a two-dimensional function by segmenting and stacking successive segments of the signal, allowing direct identification of periodic components without the need for Fourier transforms, thereby improving mass resolution and signal-to-noise ratio.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If Fourier transformation is used to analyze image-charge/current signals, then frequency domain information can be obtained, but harmonics of different orders overlap making it difficult to relate frequency to mass-to-charge ratio

Engineering Contradiction:
Improvemass resolutionVSAvoidfrequency component identification
Core Design Contradiction:
Measurement precisionVSLoss of information

Solution Approach 1:

The patent segments the time-domain signal into multiple individual oscillation cycles and displays each cycle separately in the time-frequency analysis. This segmentation allows each harmonic component to be clearly identified and distinguished, preventing the overlapping that occurs in traditional Fourier transformation where all frequency components are mixed together. By dividing the continuous signal into discrete periodic segments, the method enables precise identification of fundamental and harmonic frequencies for accurate mass-to-charge ratio determination.

Inventive Principle:
Principle #1Segmentation

2Measurement precision

If Short Time Fourier Transform is used for time-frequency analysis, then dynamics of periodic components can be analyzed, but computational complexity increases

Engineering Contradiction:
Improvedynamics analysis capabilityVSAvoidcomputational complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent replaces the complex computational machinery of Short Time Fourier Transform with a simpler visual inspection method. Instead of performing multiple Fourier transforms on segmented signals and processing the resulting spectrograms computationally, the method directly displays individual oscillation cycles in the time domain, allowing dynamics analysis through straightforward visual examination of periodic patterns. This substitution dramatically reduces computational complexity while maintaining the ability to analyze frequency dynamics.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Quantity of substance

If traditional Fourier transformation is used, then mass spectrum data can be obtained, but signal-to-noise ratio is reduced due to harmonic overlap

Engineering Contradiction:
Improvesignal-to-noise ratioVSAvoidfrequency component separation
Core Design Contradiction:
Quantity of substanceVSLoss of information

Solution Approach 1:

The patent extracts and displays individual oscillation cycles separately, taking out each periodic component from the mixed frequency spectrum. By isolating individual cycles in the time domain and displaying them separately, the method extracts clear frequency information without the harmonic overlap that degrades signal-to-noise ratio in traditional Fourier transformation. This extraction approach preserves the integrity of each frequency component while enabling their individual analysis.

Inventive Principle:
Principle #2Taking out (Extraction)

Data Source

PatentUS11410842B2Time-frequency analysis
Publication Date: 2022.08.09 SHIMADZU CORP
  • US11410842B2 patent drawing
  • US11410842B2 patent drawing
  • US11410842B2 patent drawing

AI summary

Apparatus and method for processing an image-charge/current signal for an ion(s) undergoing oscillatory motion within an ion analyser apparatus. The method comprises: obtaining a recording of the image-charge/current signal (20a-20e) in the time domain. Then, by a signal processing unit, a value for the period (T) of a periodic signal component is determined within the recorded signal. Subsequently, the recorded signal is segmented into a number of successive time segments [0;T] of duration corresponding to the period (T). These lime segments are then co-registered in a first time dimension (t1) defining the period (T). The co-registered time segments are then separated along a second time dimension (t2) transverse to the first time dimension (t1). This generates a stack of time segments collectively defining a 2-dimensional (2D) function. The 2D function varies both across the stack in the first time dimension and along the stack in the second time dimension.