Ionic Liquid Sanitizers for Persistent Surface Disinfection

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Solution Overview

Problem

Conventional sanitizers using alcohol lack persistent antimicrobial properties and residual activity, making them less effective over time in controlling microbial growth.

Innovation Solution

A disinfectant composition comprising an ionic liquid with a cationic and anionic component, formulated to provide enhanced and prolonged antimicrobial activity, where the ionic liquid is present in a range of 1% to 10% by weight, and can be applied using a wipe or dispenser for effective surface disinfection.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Duration of action of moving object

If conventional alcohol-based sanitizers are used, then immediate antimicrobial effect is achieved, but persistent antimicrobial properties and residual activity are lacking

Engineering Contradiction:
Improveduration of antimicrobial activityVSAvoidresidual antimicrobial protection
Core Design Contradiction:
Duration of action of moving objectVSReliability

Solution Approach 1:

The patent changes the chemical composition parameters from conventional alcohol-based sanitizers to ionic liquid compositions containing quaternary ammonium compounds at optimized concentrations (0.1-5% w/v), which fundamentally alters the duration and reliability characteristics of the antimicrobial action

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The invention uses composite ionic liquid formulations combining multiple components including quaternary ammonium cations, anionic surfactants, and auxiliary compounds that work synergistically to provide both immediate and persistent antimicrobial effects with residual activity on surfaces

Inventive Principle:
Principle #40Composite materials

2Duration of action of moving object

If ionic liquid concentration is increased to enhance antimicrobial activity, then prolonged antimicrobial effect is achieved, but skin irritation may increase

Engineering Contradiction:
Improveprolonged antimicrobial activityVSAvoidskin irritation
Core Design Contradiction:
Duration of action of moving objectVSObject-affected harmful factors

Solution Approach 1:

The patent optimizes the concentration parameter of ionic liquids to a specific range (0.1-5% w/v) that balances prolonged antimicrobial efficacy with acceptable skin tolerance, avoiding both under-dosing (insufficient duration) and over-dosing (excessive irritation)

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The use of ionic liquids serves as an intermediary substance that provides sustained antimicrobial release over time, reducing the need for frequent reapplication and thereby reducing cumulative skin exposure and irritation compared to conventional alcohol-based products

Inventive Principle:
Principle #24Intermediary (Mediator)

Data Source

PatentUS20230413812A1Sanitizing compositions containing ionic liquid
Publication Date: 2023.12.28 CAGE BIO INC
  • US20230413812A1 patent drawing
  • US20230413812A1 patent drawing
  • US20230413812A1 patent drawing

AI summary

Disclosed herein are sanitizing/disinfecting compositions comprising an ionic liquid comprising a choline cation and fatty acid anion for use in sanitizing or disinfecting surfaces. In some embodiments, the ionic liquid is further formulated as a surface disinfectant for inanimate surfaces.