Irradiation Therapy Apparatus with Ionization and UV Modules

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Solution Overview

Problem

Current irradiation therapy for cancer and skin diseases often results in significant DNA damage to both cancer cells and surrounding tissues, leading to side effects such as hair loss and increased cancer risk, with limited options for simultaneous administration of ultraviolet light and ionization irradiation to enhance therapeutic effects.

Innovation Solution

An apparatus combining an ionization module for emitting ionization irradiation and a UV module for emitting UVA, UVB, and UVC irradiation, allowing for simultaneous or alternate emission of these forms of radiation to induce synergistic DNA damage in living cells, potentially reducing side effects and improving treatment efficacy.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If ionization irradiation is used to treat cancer cells, then therapeutic effect is improved, but DNA damage to surrounding healthy tissues increases

Engineering Contradiction:

Improvetherapeutic effectVSAvoidDNA damage to healthy tissues

Core Design Contradiction:

ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The irradiation process is divided into two distinct modules: a UV module for initial DNA damage and an ionization module for subsequent targeted irradiation. This segmentation allows each module to perform its specific function optimally while reducing cumulative damage to healthy tissues through controlled sequential administration.

Inventive Principle:

Principle #1Segmentation

Solution Approach 2:

The UV irradiation is administered as a preliminary action before ionization irradiation. This preliminary UV exposure creates initial DNA damage that sensitizes cancer cells, making them more vulnerable to the subsequent ionization irradiation, thereby reducing the overall dose needed and minimizing damage to surrounding healthy tissues.

Inventive Principle:

Principle #10Preliminary action

2Device complexity

If UV light and ionization irradiation are administered separately, then device complexity is reduced, but treatment efficacy is limited

Engineering Contradiction:

Improvedevice structureVSAvoidtreatment efficacy

Core Design Contradiction:

Device complexityVSReliability

Solution Approach 1:

The patent combines the UV module and ionization module into a single integrated apparatus that can administer both types of irradiation simultaneously or sequentially. This merging maintains relatively simple device structure while achieving synergistic treatment effects that improve overall efficacy compared to separate administration.

Inventive Principle:

Principle #5Merging (Combining)

Solution Approach 2:

The apparatus is designed with multi-functionality, capable of administering both UV irradiation and ionization irradiation through a single device. This universal design allows flexible treatment protocols (simultaneous or sequential administration) while maintaining device simplicity and achieving enhanced therapeutic effects.

Inventive Principle:

Principle #6Universality (Multi-functionality)

3Reliability

If high doses of irradiation are used to maximize DNA damage, then treatment effectiveness is improved, but side effects such as hair loss and increased cancer risk increase

Engineering Contradiction:

Improvetreatment effectivenessVSAvoidside effects

Core Design Contradiction:

ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The treatment uses partial action by administering UV irradiation and ionization irradiation in a specific sequence and dosage combination. Rather than using high doses of a single type of irradiation, the patent employs moderate doses of each type in combination, achieving maximal therapeutic effect while minimizing excessive damage that causes side effects like hair loss and increased cancer risk.

Inventive Principle:

Principle #16Partial or excessive action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The apparatus achieves maximal DNA damage with minimal irradiation doses, inducing apoptosis or necrosis in cells, thereby offering a more effective and efficient treatment for various diseases, including cancer and skin conditions, while minimizing harm to healthy tissues.

Implementation Method 1

an ionization module adapted to emit ionization irradiation

Methodology Applied

Scientific EffectIonization irradiation: Ionisation

Implementation Method 2

a ultraviolet light source to emit UV-irradiation

Methodology Applied

Scientific EffectUltraviolet radiation: Light

Data Source

PatentUS11351393B2Apparatus for use in irradiation therapy comprising ionization module and UV-light source

Publication Date: 2022.06.07 FELDREICH CARO RUIZ AB

AI summary

The present invention relates to an apparatus (1) for use in irradiation therapy, comprising an ionization module (2) adapted to emit ionization irradiation, and a power source (4) and a control unit (5) to provide a user interface. The apparatus is characterized in that the apparatus comprises an UV module (3) adapted to emit UVA, UVB and/or UVC irradiation (9), whereby the ionization module and the UV module emit irradiation simultaneously or alternately, and the ionization module emits irradiation (8) at a wave length at least below 100 nm. The invention also relates to a use of the apparatus for radiating an object (7) and use of the apparatus and method for treatment of a mammal (7). A detector may measure and/or create an image of the irradiation (6).