Irradiation Device Fluid Verification and Dose Control
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Solution Overview
Problem
Current irradiation devices for biological fluids lack verification mechanisms to ensure that the fluid is present and ready for treatment, and fail to adjust light doses based on the actual volume or weight of the fluid, potentially leading to inadequate treatment or damage from premature exposure.
Innovation Solution
An irradiation device equipped with sensors to detect the presence and weight of biological fluid containers, a controller to verify treatment readiness, and adjust light doses accordingly, preventing premature exposure by ensuring the container is correctly placed and the fluid is treatment-ready.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If irradiation treatment is performed without verification of fluid presence and readiness, then treatment can proceed without delay, but the treatment may be inadequate or cause damage from premature exposure
Solution Approach 1:
The system performs preliminary verification actions before irradiation treatment by detecting container presence, verifying fluid readiness, and measuring fluid volume/weight. These preliminary checks ensure the fluid is properly positioned and ready for treatment before light exposure begins, preventing premature exposure while maintaining efficient workflow through automated pre-checks.
Solution Approach 2:
The verification system provides feedback to the control system about container presence, fluid readiness status, and measured fluid parameters. This feedback loop enables the system to confirm proper setup conditions are met before initiating irradiation, ensuring treatment safety while allowing the process to proceed efficiently once verification is complete.
2Manufacturing precision
If fixed light dose is used for all treatments, then the irradiation process is simple and fast, but the dose may be inadequate or excessive for varying fluid volumes
Solution Approach 1:
The system transitions from a fixed light dose approach to a dynamic, adaptive dosing system. The control system adjusts the light dose based on real-time measurements of fluid volume and weight detected by sensors. This dynamic adjustment ensures each treatment receives the precise dose required for its specific fluid quantity, improving dose accuracy while the automated nature of the adjustment maintains treatment throughput.
Solution Approach 2:
The system changes the irradiation parameter (light dose) based on measured fluid parameters (volume, weight). By dynamically modifying the light dose parameter according to the actual fluid quantity present, the system achieves precise dose delivery tailored to each treatment scenario, ensuring therapeutic effectiveness without sacrificing treatment efficiency through automated parameter adjustment.
3Reliability
If verification mechanisms are added to ensure treatment readiness, then treatment safety improves, but device complexity and operational time increase
Solution Approach 1:
The verification mechanisms perform checks in advance before irradiation begins, detecting container presence, confirming fluid readiness, and measuring parameters proactively. By completing these verification actions beforehand, the system ensures treatment safety without causing delays during the actual irradiation process, as verification is finished prior to treatment initiation.
Solution Approach 2:
The verification system operates autonomously without requiring manual intervention or additional operational steps from the user. Sensors automatically detect container presence and fluid parameters, and the control system autonomously processes verification information and adjusts treatment parameters. This self- verifying capability improves treatment safety while minimizing added operational time, as the system performs checks automatically as part of the treatment workflow.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Ensures accurate and safe treatment of biological fluids by verifying the presence and weight of the fluid, adjusting light doses, and preventing premature exposure, thereby maintaining the integrity and effectiveness of the treatment process.
Implementation Method 1
detecting the weight of the container of biological fluid
Implementation Method 2
an irradiation device with one or more light sources... treatment of a blood product that has been combined with a photochemical agent for activation when subjected to light
Implementation Method 3
one or more light sources and a UV sensor(s) that measure the amount of light being delivered to the biological fluid
Data Source
AI summary
Systems and method for verifying the timely placement of a container of biolocal cells or fluid within a treatment chamber of a biological fluid treating device are disclosed. The systems and methods utilize a sensor that detects the presence of a container at an appropriate and pre-determined time and, optionally, detects the weight of the container and cells.